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Differential effects of skilled reaching training on the temporal and spatial organization of somatosensory input to cortical and striatal motor circuits
Integrative Neurophysiology and Neurotechnology, Department of Experimental Medical Sciences, Lund University, Lund, Sweden.
Umeå University, Faculty of Medicine, Department of Integrative Medical Biology (IMB).ORCID iD: 0000-0002-2786-7910
Integrative Neurophysiology and Neurotechnology, Department of Experimental Medical Sciences, Lund University, Lund, Sweden.
Integrative Neurophysiology and Neurotechnology, Department of Experimental Medical Sciences, Lund University, Lund, Sweden.
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2022 (English)In: Journal of Neurophysiology, ISSN 0022-3077, E-ISSN 1522-1598, Vol. 127, no 1, p. 225-238Article in journal (Refereed) Published
Abstract [en]

It has been hypothesized that to perform sensorimotor transformations efficiently, somatosensory information being fed back to a particular motor circuit is organized in accordance with the mechanical loading patterns of the skin that result from the motor activity generated by that circuit. Rearrangements of sensory information to different motor circuits could in this respect constitute a key component of sensorimotor learning. We here explored whether the organization of tactile input from the plantar forepaw of the rat to cortical and striatal circuits is affected by a period of extensive sensorimotor training in a skilled reaching and grasping task. Our data show that the representation of tactile stimuli in terms of both temporal and spatial response patterns changes as a consequence of the training and that spatial changes particularly involve the primary motor cortex. Based on the observed reorganization, we propose that reshaping of the spatiotemporal representation of the tactile afference to motor circuits is an integral component of the learning process that underlies skill acquisition in reaching and grasping.

Place, publisher, year, edition, pages
American Physiological Society , 2022. Vol. 127, no 1, p. 225-238
Keywords [en]
Corticostriatal, In vivo, Learning, Neurophysiology
National Category
Neurosciences Physiology
Identifiers
URN: urn:nbn:se:umu:diva-192265DOI: 10.1152/jn.00464.2021ISI: 000743746500005PubMedID: 34936519Scopus ID: 2-s2.0-85123790821OAI: oai:DiVA.org:umu-192265DiVA, id: diva2:1643917
Funder
Forte, Swedish Research Council for Health, Working Life and Welfare, 2016-07213Swedish Research Council, 2018-02717Swedish Research Council, 325-2011-6441Available from: 2022-03-11 Created: 2022-03-11 Last updated: 2022-03-11Bibliographically approved

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Censoni, LucianoPetersson, Per

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