Umeå universitets logga

umu.sePublikationer
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Can We Cluster ICU Treatment Strategies for Traumatic Brain Injury by Hospital Treatment Preferences?
Visa övriga samt affilieringar
2022 (Engelska)Ingår i: Neurocritical Care, ISSN 1541-6933, E-ISSN 1556-0961, Vol. 36, nr 3, s. 846-856Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

BACKGROUND: In traumatic brain injury (TBI), large between-center differences in treatment and outcome for patients managed in the intensive care unit (ICU) have been shown. The aim of this study is to explore if European neurotrauma centers can be clustered, based on their treatment preference in different domains of TBI care in the ICU.

METHODS: Provider profiles of centers participating in the Collaborative European Neurotrauma Effectiveness Research in TBI study were used to assess correlations within and between the predefined domains: intracranial pressure monitoring, coagulation and transfusion, surgery, prophylactic antibiotics, and more general ICU treatment policies. Hierarchical clustering using Ward's minimum variance method was applied to group data with the highest similarity. Heat maps were used to visualize whether hospitals could be grouped to uncover types of hospitals adhering to certain treatment strategies.

RESULTS: Provider profiles were available from 66 centers in 20 different countries in Europe and Israel. Correlations within most of the predefined domains varied from low to high correlations (mean correlation coefficients 0.2-0.7). Correlations between domains were lower, with mean correlation coefficients of 0.2. Cluster analysis showed that policies could be grouped, but hospitals could not be grouped based on their preference.

CONCLUSIONS: Although correlations between treatment policies within domains were found, the failure to cluster hospitals indicates that a specific treatment choice within a domain is not a proxy for other treatment choices within or outside the domain. These results imply that studying the effects of specific TBI interventions on outcome can be based on between-center variation without being substantially confounded by other treatments.

TRIAL REGISTRATION: We do not report the results of a health care intervention.

Ort, förlag, år, upplaga, sidor
Springer, 2022. Vol. 36, nr 3, s. 846-856
Nyckelord [en]
Between-hospital variation, Comparative effectiveness research, Provider profiling, Traumatic brain injury
Nationell ämneskategori
Neurologi
Identifikatorer
URN: urn:nbn:se:umu:diva-193099DOI: 10.1007/s12028-021-01386-yISI: 000727129000001PubMedID: 34873673Scopus ID: 2-s2.0-85130632973OAI: oai:DiVA.org:umu-193099DiVA, id: diva2:1644466
Forskningsfinansiär
EU, FP7, Sjunde ramprogrammetTillgänglig från: 2022-03-14 Skapad: 2022-03-14 Senast uppdaterad: 2024-03-26Bibliografiskt granskad

Open Access i DiVA

fulltext(1413 kB)93 nedladdningar
Filinformation
Filnamn FULLTEXT02.pdfFilstorlek 1413 kBChecksumma SHA-512
1a55dac94a9d026e9511a9e0d4586280ff077a54a5a3cdd35604fd3435d9db9e281b4da60aeddf653c01bd4bb7e65cbe7324c873a86e5147a2e8309e1d133470
Typ fulltextMimetyp application/pdf

Övriga länkar

Förlagets fulltextPubMedScopus

Person

Koskinen, Lars-Owe D.

Sök vidare i DiVA

Av författaren/redaktören
Koskinen, Lars-Owe D.
Av organisationen
Neurovetenskaper
I samma tidskrift
Neurocritical Care
Neurologi

Sök vidare utanför DiVA

GoogleGoogle Scholar
Totalt: 112 nedladdningar
Antalet nedladdningar är summan av nedladdningar för alla fulltexter. Det kan inkludera t.ex tidigare versioner som nu inte längre är tillgängliga.

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
Totalt: 157 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf