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Long-term outcome after routine surgery for pelvic organ prolapse: a national register-based cohort study
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Obstetrics and Gynecology.ORCID iD: 0000-0003-3988-6323
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Obstetrics and Gynecology.
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Obstetrics and Gynecology.ORCID iD: 0000-0002-4988-1967
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Obstetrics and Gynecology.
2022 (English)In: International Urogynecology Journal, ISSN 0937-3462, E-ISSN 1433-3023, Vol. 33, no 7, p. 1863-1873Article in journal (Refereed) Published
Abstract [en]

Introduction and hypothesis: Pelvic organ prolapse (POP) is common, and women have an estimated 12–19% lifetime risk for needing POP surgery. Aims were to measure re-operation rates up to 10 years after POP surgery and patient-reported outcomes (PROMs) 5 years after a first-time operation for POP.

Methods: This is a cohort study using the Swedish National Quality Register for Gynaecological Surgery (GynOp). We retrieved information from 32,086 POP-operated women up to 10 years later. After validation, a web-based PROM questionnaire was sent to 4380 women who 5 years previously had standard POP surgery. Main outcome measures were reoperations due to a relapse of prolapse and PROMs 5 years after the primary operation.

Results: Among women operated for all types of POP, 11% had re-operations 5 years later and an additional 4% 10 years later, with similar frequencies for various compartments/types of surgery. PROMs yielded a 75% response rate after 5 years. Cure rate was 68% for anterior, 70% for posterior, and 74% for combined anterior-posterior native repairs. Patient satisfaction exceeded 70%, and symptom reduction was still significant after 5 years (p < 0.0001).

Conclusions: Following primary prolapse surgery, re-operation rates are low, even after 10 years. A web-based survey for follow-up of PROMs after POP surgery is feasible and yields a high response rate after 5 years. The subjective cure rate after primary POP operations is high, with reduced symptoms and satisfied patients regardless of compartment. Standard prolapse surgery with native tissue repair produces satisfactory long-term results.

Place, publisher, year, edition, pages
Springer, 2022. Vol. 33, no 7, p. 1863-1873
Keywords [en]
Follow-up studies, Kaplan-Meier estimates, Pelvic organ prolapse, Population register, Surveys and questionnaires
National Category
Obstetrics, Gynecology and Reproductive Medicine Surgery
Research subject
Obstetrics and Gynaecology
Identifiers
URN: urn:nbn:se:umu:diva-193595DOI: 10.1007/s00192-022-05156-yISI: 000771388500002PubMedID: 35312802Scopus ID: 2-s2.0-85126814359OAI: oai:DiVA.org:umu-193595DiVA, id: diva2:1651881
Funder
Swedish Association of Local Authorities and RegionsAvailable from: 2022-04-13 Created: 2022-04-13 Last updated: 2022-12-19Bibliographically approved

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Nüssler, EmilGranåsen, GabrielBixo, MarieLöfgren, Mats

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Obstetrics, Gynecology and Reproductive MedicineSurgery

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