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Major complications and mortality after ventral hernia repair: An eleven-year Swedish nationwide cohort study
Umeå universitet, Medicinska fakulteten, Institutionen för kirurgisk och perioperativ vetenskap, Kirurgi.
Umeå universitet, Medicinska fakulteten, Institutionen för kirurgisk och perioperativ vetenskap, Kirurgi.
Umeå universitet, Medicinska fakulteten, Institutionen för kirurgisk och perioperativ vetenskap, Kirurgi. Umeå universitet, Medicinska fakulteten, Institutionen för diagnostik och intervention.ORCID-id: 0000-0001-5838-9133
Umeå universitet, Medicinska fakulteten, Institutionen för kirurgisk och perioperativ vetenskap, Kirurgi. Umeå universitet, Medicinska fakulteten, Institutionen för diagnostik och intervention.ORCID-id: 0000-0002-3806-2114
2022 (Engelska)Ingår i: BMC Surgery, E-ISSN 1471-2482, Vol. 22, artikel-id 426Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Background and aims: Ventral hernia repair is one of the most common surgical procedures performed worldwide. Despite the large volume, consensus is lacking regarding indications for repair or choice of surgical method used for reconstruction. The aim of this study was to explore the risk for major complications and mortality in ventral hernia repair using data from a nationwide patient register.

Method: Patient data of individuals over 18 years of age who had a ventral hernia procedure between 2004 and 2014 were retrieved from the Patient Register kept by the Swedish National Board of Health and Welfare. After exclusion of patients with concomitant bowel surgery, 45 676 primary surgical admissions were included. Procedures were dichotomised into laparoscopic and open surgery, and stratified for primary and incisional hernias.

Results: A total of 45 676 admissions were analysed. The material comprised 36% (16 670) incisional hernias and 64% (29 006) primary hernias. Women had a higher risk for reoperation during index admission after primary hernia repair (OR 1.84 (1.29–2.62)). Forty-three patients died of complications within 30 days of index surgery. Patients aged 80 years and older had a 2.5 times higher risk for a complication leading to reoperation, and a 12-fold higher mortality risk than patients aged 70–79 years.

Conclusion: Age is the dominant mortality risk factor in ventral hernia repair. Laparoscopic surgery was associated with a lower risk for reoperation during index admission. Reoperation seems to be a valid outcome variable, while registration of complications is generally poor in this type of cohort.

Ort, förlag, år, upplaga, sidor
BioMed Central (BMC), 2022. Vol. 22, artikel-id 426
Nyckelord [en]
Ventral hernia, Hernia repair, Risk factor, Complication, Mortality
Nationell ämneskategori
Kirurgi
Forskningsämne
kirurgi
Identifikatorer
URN: urn:nbn:se:umu:diva-199800DOI: 10.1186/s12893-022-01873-9ISI: 000898752200001PubMedID: 36514042Scopus ID: 2-s2.0-85143755325OAI: oai:DiVA.org:umu-199800DiVA, id: diva2:1699781
Anmärkning

Originally included in thesis in manuscript form. 

Tillgänglig från: 2022-09-29 Skapad: 2022-09-29 Senast uppdaterad: 2025-03-26Bibliografiskt granskad
Ingår i avhandling
1. Minimising risk and optimising technique in ventral hernia repair
Öppna denna publikation i ny flik eller fönster >>Minimising risk and optimising technique in ventral hernia repair
2022 (Engelska)Doktorsavhandling, sammanläggning (Övrigt vetenskapligt)
Alternativ titel[sv]
Minimera risk och optimera teknik vid kirurgi för främre bukväggsbråck
Abstract [en]

Background: Abdominal wall hernia is a common pathology and adverse events related to hernia repair is thus a topic of considerable importance. Hernia is a disease that affect both sexes and people of all ages.

The thesis is based upon four papers. Study I, II and III are analysing complications related to ventral hernia repair. Study IV is a multicentre trial.

Aims:

  1. to analyse risk factors in open and minimally invasive ventral hernia repair
  2. to improve the technique of laparoscopic ventral hernia repair.

Results: Study I: Hernia aperture size was the most important risk factor for serious complication after hernia repair. Study II: Inadvertent enterotomy occurred during 25 repairs and in these cases laparoscopic repair was clearly overrepresented (p<0.001). Study III: A total of 45 676 repairs were analysed. We found that patients 80 years and older had a 2.5 times higher risk for complication leading to reoperation, and a 12-fold higher mortality risk than patients aged 70-79 years. Study IV: Closure of the hernia aperture before mesh application does not decrease hernia site complications in small to medium-sized midline hernias at twelve-month follow-up (p = 0.73).

Conclusions: Hernia aperture size is the leading risk factor for serious complication after ventral hernia repair. Accidental enterotomy is more common during laparoscopic repair. Risk of death after ventral hernia repair dramatically increases in the geriatric patient. Time should not be wasted on closure of small to medium-sized hernia apertures in the midline before laparoscopic application of a mesh.

Ort, förlag, år, upplaga, sidor
Umeå: Umeå university, 2022. s. 58
Serie
Umeå University medical dissertations, ISSN 0346-6612 ; 2198
Nyckelord
hernia, complications, ventral hernia repair, laparoscopy, RCT, incisional hernia
Nationell ämneskategori
Kirurgi
Forskningsämne
kirurgi
Identifikatorer
urn:nbn:se:umu:diva-199808 (URN)978-91-7855-867-4 (ISBN)978-91-7855-868-1 (ISBN)
Disputation
2022-10-28, Aula Aronia, By103, plan 5, Skellefteå Lasarett, Skellefteå, 09:00 (Svenska)
Opponent
Handledare
Tillgänglig från: 2022-10-07 Skapad: 2022-09-29 Senast uppdaterad: 2022-12-07Bibliografiskt granskad

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Lindmark, MikaelLöwenmark, ThyraStrigård, KarinGunnarsson, Ulf

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