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Minimising risk and optimising technique in ventral hernia repair
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences, Surgery.
2022 (English)Doctoral thesis, comprehensive summary (Other academic)Alternative title
Minimera risk och optimera teknik vid kirurgi för främre bukväggsbråck (Swedish)
Abstract [en]

Background: Abdominal wall hernia is a common pathology and adverse events related to hernia repair is thus a topic of considerable importance. Hernia is a disease that affect both sexes and people of all ages.

The thesis is based upon four papers. Study I, II and III are analysing complications related to ventral hernia repair. Study IV is a multicentre trial.

Aims:

  1. to analyse risk factors in open and minimally invasive ventral hernia repair
  2. to improve the technique of laparoscopic ventral hernia repair.

Results: Study I: Hernia aperture size was the most important risk factor for serious complication after hernia repair. Study II: Inadvertent enterotomy occurred during 25 repairs and in these cases laparoscopic repair was clearly overrepresented (p<0.001). Study III: A total of 45 676 repairs were analysed. We found that patients 80 years and older had a 2.5 times higher risk for complication leading to reoperation, and a 12-fold higher mortality risk than patients aged 70-79 years. Study IV: Closure of the hernia aperture before mesh application does not decrease hernia site complications in small to medium-sized midline hernias at twelve-month follow-up (p = 0.73).

Conclusions: Hernia aperture size is the leading risk factor for serious complication after ventral hernia repair. Accidental enterotomy is more common during laparoscopic repair. Risk of death after ventral hernia repair dramatically increases in the geriatric patient. Time should not be wasted on closure of small to medium-sized hernia apertures in the midline before laparoscopic application of a mesh.

Place, publisher, year, edition, pages
Umeå: Umeå university , 2022. , p. 58
Series
Umeå University medical dissertations, ISSN 0346-6612 ; 2198
Keywords [en]
hernia, complications, ventral hernia repair, laparoscopy, RCT, incisional hernia
National Category
Surgery
Research subject
Surgery
Identifiers
URN: urn:nbn:se:umu:diva-199808ISBN: 978-91-7855-867-4 (print)ISBN: 978-91-7855-868-1 (electronic)OAI: oai:DiVA.org:umu-199808DiVA, id: diva2:1699812
Public defence
2022-10-28, Aula Aronia, By103, plan 5, Skellefteå Lasarett, Skellefteå, 09:00 (Swedish)
Opponent
Supervisors
Available from: 2022-10-07 Created: 2022-09-29 Last updated: 2022-12-07Bibliographically approved
List of papers
1. Risk factors for surgical complications in ventral hernia repair
Open this publication in new window or tab >>Risk factors for surgical complications in ventral hernia repair
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2018 (English)In: World Journal of Surgery, ISSN 0364-2313, E-ISSN 1432-2323, Vol. 42, no 11, p. 3528-3536Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: The aim of this study was to identify risk factors for an adverse event, i.e. early surgical complication, need for ICU care and readmission, following ventral hernia repair. Our hypothesis was that there is an association between an increased complication rate following ventral hernia repair and specific factors, including hernia size, BMI > 35, concomitant bowel surgery, ASA-class, age, gender and method of hernia repair.

METHODS: Data from a hernia database with prospectively entered data on 408 patients operated for ventral hernia between 2007 and 2014 at two Swedish university hospitals were analysed. A 3-month follow-up of complications, need for intensive care and readmission, was performed by reviewing the medical records.

RESULTS: Eighty-one of 408 patients (20%) had a registered complication. Fifty-eight (14%) of these were classed as Clavien I-IIIa, and in 19 cases a Clavien IIIb-IV complication was reported. Large hernia size was associated with increased risk for early complication. A Kendall Tau test analysis revealed a proportional relationship between hernia size and modified Clavien outcome class (p < 0.001). Morbid obesity, ASA-class, method, hernia recurrence, age and concomitant bowel surgery were not statistically significant predictors of adverse events.

CONCLUSIONS: Assessment of hernia aperture size is of great importance in the preoperative evaluation of ventral hernia patients to consider risk for post-operative complications. These results suggest a careful attitude when applying watchful waiting concepts and when postponing hernia surgery to achieve weight loss. A delaying attitude may result in increased risk of complications caused by increasing hernia size.

Place, publisher, year, edition, pages
New York: Springer, 2018
Keywords
incisional hernia, controlled trial, mesh repair, surgery, multicenter, cohort, safe, CT
National Category
Surgery
Identifiers
urn:nbn:se:umu:diva-148354 (URN)10.1007/s00268-018-4642-6 (DOI)000446776000009 ()29700567 (PubMedID)2-s2.0-85045925703 (Scopus ID)
Funder
Västerbotten County Council, VLL-567051
Available from: 2018-06-04 Created: 2018-06-04 Last updated: 2024-04-09Bibliographically approved
2. Patient Reported Injuries After Ventral Hernia Repair
Open this publication in new window or tab >>Patient Reported Injuries After Ventral Hernia Repair
2019 (English)In: Scandinavian Journal of Surgery, ISSN 1457-4969, E-ISSN 1799-7267, Vol. 108, no 1, p. 30-35Article in journal (Refereed) Published
Abstract [en]

BACKGROUND AND AIMS: The Swedish National Patient Insurance Company (LÖF) can compensate patients who believe they have been exposed to an avoidable injury or malpractice in healthcare. Its register covers 95% of Swedish healthcare providers.

MATERIAL AND METHODS: Data on patients operated for primary or incisional ventral hernia in Sweden between 2010 and 2015 and who had filed a claim, were retrieved from LÖF. A total of 290 cases were identified and included. Files include a copy of records, relevant imaging, and an expert advisor's opinion.

RESULTS: Inadvertent enterotomy occurred during 25 repairs and in these cases, laparoscopic repair was clearly overrepresented ( p  < 0.001). Complications related to the surgical site (infection and ugly scar) were predominantly related to open repairs ( p  < 0.001). Twenty percentage (57/290) of the claims were directly related to an anesthetic mishap. Univariate ordinal regression showed that the odds of receiving a high reimbursement was significantly increased if laparoscopic repair was performed p  < 0.001 (odds ratio: 0.37; 95% confidence interval: 0.21-0.65). Sixty-three percentage of claims were filed by women.

CONCLUSION: Inadvertent enterotomy is overrepresented, and the probability that a claim filed for an avoidable injury leads to high reimbursement is greater if laparoscopic repair is performed rather than open ventral hernia repair. The high amount of injuries related to general anesthesia during umbilical hernia repair may be reduced with an increased proportion executed in local anesthesia.

Place, publisher, year, edition, pages
Sage Publications, 2019
Keywords
Ventral hernia, enterotomy, hernia repair, iatrogenic patient injury, insurance, laparoscopic repair, local anesthesia
National Category
Surgery
Identifiers
urn:nbn:se:umu:diva-150228 (URN)10.1177/1457496918783727 (DOI)000461561500005 ()29966500 (PubMedID)2-s2.0-85049627520 (Scopus ID)
Funder
Västerbotten County Council, VLL-675981
Available from: 2018-07-20 Created: 2018-07-20 Last updated: 2024-04-09Bibliographically approved
3. Major complications and mortality after ventral hernia repair: An eleven-year Swedish nationwide cohort study
Open this publication in new window or tab >>Major complications and mortality after ventral hernia repair: An eleven-year Swedish nationwide cohort study
2022 (English)In: BMC Surgery, E-ISSN 1471-2482, Vol. 22, article id 426Article in journal (Refereed) Published
Abstract [en]

Background and aims: Ventral hernia repair is one of the most common surgical procedures performed worldwide. Despite the large volume, consensus is lacking regarding indications for repair or choice of surgical method used for reconstruction. The aim of this study was to explore the risk for major complications and mortality in ventral hernia repair using data from a nationwide patient register.

Method: Patient data of individuals over 18 years of age who had a ventral hernia procedure between 2004 and 2014 were retrieved from the Patient Register kept by the Swedish National Board of Health and Welfare. After exclusion of patients with concomitant bowel surgery, 45 676 primary surgical admissions were included. Procedures were dichotomised into laparoscopic and open surgery, and stratified for primary and incisional hernias.

Results: A total of 45 676 admissions were analysed. The material comprised 36% (16 670) incisional hernias and 64% (29 006) primary hernias. Women had a higher risk for reoperation during index admission after primary hernia repair (OR 1.84 (1.29–2.62)). Forty-three patients died of complications within 30 days of index surgery. Patients aged 80 years and older had a 2.5 times higher risk for a complication leading to reoperation, and a 12-fold higher mortality risk than patients aged 70–79 years.

Conclusion: Age is the dominant mortality risk factor in ventral hernia repair. Laparoscopic surgery was associated with a lower risk for reoperation during index admission. Reoperation seems to be a valid outcome variable, while registration of complications is generally poor in this type of cohort.

Place, publisher, year, edition, pages
BioMed Central (BMC), 2022
Keywords
Ventral hernia, Hernia repair, Risk factor, Complication, Mortality
National Category
Surgery
Research subject
Surgery
Identifiers
urn:nbn:se:umu:diva-199800 (URN)10.1186/s12893-022-01873-9 (DOI)000898752200001 ()36514042 (PubMedID)2-s2.0-85143755325 (Scopus ID)
Note

Originally included in thesis in manuscript form. 

Available from: 2022-09-29 Created: 2022-09-29 Last updated: 2025-03-26Bibliographically approved
4. Primary fascial closure in laparoscopic ventral hernia repair does not reduce hernia site complication rate: the PROSECO-trial
Open this publication in new window or tab >>Primary fascial closure in laparoscopic ventral hernia repair does not reduce hernia site complication rate: the PROSECO-trial
Show others...
(English)Manuscript (preprint) (Other academic)
National Category
Surgery
Research subject
Surgery
Identifiers
urn:nbn:se:umu:diva-199801 (URN)
Available from: 2022-09-29 Created: 2022-09-29 Last updated: 2022-09-29

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