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Estimating a social value set for EQ-5D-5L in Sweden
Umeå University, Faculty of Medicine, Department of Epidemiology and Global Health. Research Group Health Outcomes and Economic Evaluation, Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Stockholm, Sweden.ORCID iD: 0000-0001-5948-3025
Umeå University, Faculty of Medicine, Department of Epidemiology and Global Health.ORCID iD: 0000-0001-8043-0411
Umeå University, Faculty of Medicine, Department of Epidemiology and Global Health.ORCID iD: 0000-0002-3975-4868
Umeå University, Faculty of Medicine, Department of Epidemiology and Global Health.ORCID iD: 0000-0002-1633-2179
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2022 (English)In: Health and Quality of Life Outcomes, ISSN 1477-7525, E-ISSN 1477-7525, Vol. 20, no 1, article id 167Article in journal (Refereed) Published
Abstract [en]

Background: The study aims to elicit a value set based on the EQ-VT for the EQ-5D-5L that can be used to support decision-making in Sweden.

Methods: Participants were recruited from the general population based on age, sex and urban/rural area quota sampling from five regions across Sweden. In total, 785 interviews were conducted from February 2020 to April 2021 using the EQVT 2.1 protocol, and both composite time trade-off (c-TTO) and discrete choice experiments (DCE) were used to elicit health preferences. A variety of models have been tested for the c-TTO data (generalized least square, Tobit, heteroskedastic models) and DCE data (conditional logit model), as well as the combined c-TTO and DCE data (hybrid modelling). Model selection was based on theoretical considerations, logical consistency of the parameter estimates, and significance of the parameters (p = 0.05). Model goodness-of-fit was assessed by AIC and BIC, and prediction accuracy was assessed in terms of mean absolute error. The predictions for the EQ-5D-5L health states between models were compared using scatterplots.

Results: The preferred model for generating the value set was the heteroskedastic model based on the c-TTO data, with the health utilities ranging from -0.31 for the worst (55,555) to 1 for the best (11111) EQ-5D-5L states.

Conclusion: This is the first c-TTO-based social value set for the EQ-5D-5L in Sweden. It can be used to support the health utility estimation in economic evaluations for reimbursement decision making in Sweden.

Place, publisher, year, edition, pages
BioMed Central (BMC), 2022. Vol. 20, no 1, article id 167
Keywords [en]
EQ-5D-5L, Social value, Value set
National Category
Public Health, Global Health, Social Medicine and Epidemiology Health Care Service and Management, Health Policy and Services and Health Economy
Identifiers
URN: urn:nbn:se:umu:diva-202242DOI: 10.1186/s12955-022-02083-wISI: 000903410600003PubMedID: 36564844Scopus ID: 2-s2.0-85144637922OAI: oai:DiVA.org:umu-202242DiVA, id: diva2:1725322
Available from: 2023-01-10 Created: 2023-01-10 Last updated: 2023-09-05Bibliographically approved

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Sun, SunChuang, Ling-HsiangSahlen, Klas-GöranLindholm, LarsNorström, Fredrik

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Health and Quality of Life Outcomes
Public Health, Global Health, Social Medicine and EpidemiologyHealth Care Service and Management, Health Policy and Services and Health Economy

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