Temporal dementia and cognitive impairment trends in the very old in the 21st centuryVisa övriga samt affilieringar
2023 (Engelska)Ingår i: Journal of Alzheimer's Disease, ISSN 1387-2877, E-ISSN 1875-8908, Vol. 93, nr 1, s. 61-74Artikel i tidskrift (Refereegranskat) Published
Abstract [en]
BACKGROUND: Long-increasing dementia incidence and prevalence trends may be shifting. Whether such shifts have reached the very old is unknown.
OBJECTIVE: To investigate temporal trends in the incidence of dementia and cognitive impairment and prevalence of dementia, cognitive impairment, Alzheimer's disease, vascular dementia, and unclassified dementia among 85-, 90-, and ≥ 95-year-olds in Sweden during 2000-2017.
METHODS: This study was conducted with Umeå 85 + /Gerontological Regional Database data from 2182 85-, 90-, and ≥ 95-year-olds in Sweden collected in 2000-2017. Using logistic regression, trends in the cumulative 5-year incidences of dementia and cognitive impairment; prevalences of dementia, cognitive impairment, Alzheimer's disease, and vascular dementia; and Mini-Mental State Examination thresholds for dementia diagnosis were estimated.
RESULTS: Dementia and cognitive impairment incidences decreased in younger groups, which generally showed more-positive temporal trends. The prevalences of overall dementia, cognitive impairment, and Alzheimer's disease were stable or increasing; longer disease durations and increasing dementia subtype classification success may mask positive changes in incidences. Vascular dementia increased while unclassified dementia generally decreased. CONCLUSION: The cognitive health of the very old may be changing in the 21st century, possibly indicating a trend break.
Ort, förlag, år, upplaga, sidor
IOS Press, 2023. Vol. 93, nr 1, s. 61-74
Nyckelord [en]
Aged 80 and over, Alzheimer’s disease, cognition disorders, cohort studies, cross-sectional studies, dementia, epidemiologic studies, longitudinal studies, neurocognitive disorders, vascular dementia
Nationell ämneskategori
Geriatrik
Identifikatorer
URN: urn:nbn:se:umu:diva-209294DOI: 10.3233/JAD-220915ISI: 000980906000005PubMedID: 36938733Scopus ID: 2-s2.0-85159555239OAI: oai:DiVA.org:umu-209294DiVA, id: diva2:1764161
Forskningsfinansiär
Vetenskapsrådet, K2014–99X-22610–01–6Umeå universitetRegion VästerbottenDemensförbundet2023-06-082023-06-082023-09-05Bibliografiskt granskad