Umeå University's logo

umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Minor variations in multicellular life cycles have major effects on adaptation
Umeå University, Faculty of Science and Technology, Department of Mathematics and Mathematical Statistics.
Umeå University, Faculty of Science and Technology, Department of Mathematics and Mathematical Statistics. Advancing Systems Analysis Program, International Institute for Applied Systems Analysis (IIASA), Laxenburg, Austria; Complexity Science and Evolution Unit, Okinawa Institute of Science and Technology Graduate University, Japan.ORCID iD: 0000-0001-9862-816x
Umeå University, Faculty of Science and Technology, Department of Mathematics and Mathematical Statistics.ORCID iD: 0000-0002-6569-5793
2023 (English)In: PloS Computational Biology, ISSN 1553-734X, E-ISSN 1553-7358, Vol. 19, no 4, article id e1010698Article in journal (Refereed) Published
Abstract [en]

Multicellularity has evolved several independent times over the past hundreds of millions of years and given rise to a wide diversity of complex life. Recent studies have found that large differences in the fundamental structure of early multicellular life cycles can affect fitness and influence multicellular adaptation. Yet, there is an underlying assumption that at some scale or categorization multicellular life cycles are similar in terms of their adaptive potential. Here, we consider this possibility by exploring adaptation in a class of simple multicellular life cycles of filamentous organisms that only differ in one respect, how many daughter filaments are produced. We use mathematical models and evolutionary simulations to show that despite the similarities, qualitatively different mutations fix. In particular, we find that mutations with a tradeoff between cell growth and group survival, i.e. "selfish" or "altruistic" traits, spread differently. Specifically, altruistic mutations more readily spread in life cycles that produce few daughters while in life cycles producing many daughters either type of mutation can spread depending on the environment. Our results show that subtle changes in multicellular life cycles can fundamentally alter adaptation.

Place, publisher, year, edition, pages
2023. Vol. 19, no 4, article id e1010698
National Category
Evolutionary Biology
Identifiers
URN: urn:nbn:se:umu:diva-209284DOI: 10.1371/journal.pcbi.1010698ISI: 000974421200004PubMedID: 37083675Scopus ID: 2-s2.0-85159546634OAI: oai:DiVA.org:umu-209284DiVA, id: diva2:1764276
Funder
Swedish Research Council, 2018-0363Available from: 2023-06-08 Created: 2023-06-08 Last updated: 2023-06-08Bibliographically approved

Open Access in DiVA

fulltext(2238 kB)55 downloads
File information
File name FULLTEXT01.pdfFile size 2238 kBChecksum SHA-512
97e0d6a2aa8f7fd5b4b4030072da7d0ae5442fd7302030eb4cdcdf6d0fa8e5d1b4c155d9e668d6ce72d9eceaf8f6e8b5c93d9deb84207a8a83fce13c470fbca0
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMedScopus

Authority records

Isaksson, HannaBrännström, ÅkeLibby, Eric

Search in DiVA

By author/editor
Isaksson, HannaBrännström, ÅkeLibby, Eric
By organisation
Department of Mathematics and Mathematical Statistics
In the same journal
PloS Computational Biology
Evolutionary Biology

Search outside of DiVA

GoogleGoogle Scholar
Total: 55 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 217 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf