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Early Experiences on using Triplet Networks for Histological Subtype Classification in Non-Small Cell Lung Cancer
Humanitas University, Department of Biomedical Sciences, Milan, Italy.
Humanitas University, Department of Biomedical Sciences, Milan, Italy; IRCCS Humanitas Research Hospital, Milan, Italy.
Humanitas University, Department of Biomedical Sciences, Milan, Italy; IRCCS Humanitas Research Hospital, Milan, Italy.
Umeå University, Faculty of Medicine, Department of Radiation Sciences, Radiation Physics. Humanitas University, Department of Biomedical Sciences, Milan, Italy; Campus Bio-Medico University of Rome, Research Unit of Computer Systems and Bioinformatics, Rome, Italy.ORCID iD: 0000-0003-2621-072X
2023 (English)In: 2023 IEEE 36th International Symposium on Computer-Based Medical Systems (CBMS): Proceedings / [ed] João Rafael Almeida; Myra Spiliopoulou; Jose Alberto Benitez Andrades; Giuseppe Placidi; Alejandro Rodríguez González; Rosa Sicilia; Bridget Kane, IEEE, 2023, p. 832-837Conference paper, Published paper (Refereed)
Abstract [en]

Lung cancer has the highest mortality rate among tumours and an accurate pathological assessment is crucial to deliver personalized treatments to patients. The gold standard for pathological assessment requires invasive procedures, which are not always possible and might cause clinical complications. Therefore, in the last years, efforts have been directed towards the development of machine and deep learning approaches for virtual biopsy, which leverage routinely collected CT scans. However, in many cases, the available datasets are limited in size, an issue that limits the training of any model. In this paper, we investigate if triplet networks can cope with this limitation: they are a class of neural networks that uses the same weights while working in tandem on three different input vectors to minimize the loss function. In particular, on a dataset including 87 CT scans collected from patients suffering from non-small cell lung cancer, we experimentally compare triplet networks against plain deep networks when performing histological subtype classification. The results show that the former outperforms the latter in almost all experiments.

Place, publisher, year, edition, pages
IEEE, 2023. p. 832-837
Series
Proceedings - IEEE Symposium on Computer-Based Medical Systems., ISSN 1063-7125
Keywords [en]
artificial intelligence, medical imaging, siamese neural networks, virtual biopsy
National Category
Radiology, Nuclear Medicine and Medical Imaging
Identifiers
URN: urn:nbn:se:umu:diva-212828DOI: 10.1109/CBMS58004.2023.00328ISI: 001037777900146Scopus ID: 2-s2.0-85166468762ISBN: 9798350312249 (electronic)OAI: oai:DiVA.org:umu-212828DiVA, id: diva2:1788253
Conference
36th IEEE International Symposium on Computer-Based Medical Systems, CBMS 2023, L'Aquila, Italy, June 22-24, 2023
Available from: 2023-08-16 Created: 2023-08-16 Last updated: 2025-04-24Bibliographically approved

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Soda, Paolo

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