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Practice patterns in diagnostics, staging, and management strategies of gallbladder cancer among Nordic tertiary centers
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2023 (English)In: Scandinavian Journal of Surgery, ISSN 1457-4969, E-ISSN 1799-7267, Vol. 112, no 3, p. 147-156Article in journal (Refereed) Published
Abstract [en]

Background and objective: Gallbladder cancer (GBC) is a rare malignancy in the Nordic countries and no common Nordic treatment guidelines exist. This study aimed to characterize the current diagnostic and treatment strategies in the Nordic countries and disclose differences in these strategies.

Methods: This was a survey study with a cross-sectional questionnaire of all 19 university hospitals providing curative-intent surgery for GBC in Sweden, Norway, Denmark, and Finland.

Results: In all Nordic countries except Sweden, neoadjuvant/downstaging chemotherapy was used in GBC patients. In T1b and T2, majority of the centers (15-18/19) performed extended cholecystectomy. In T3, majority of the centers (13/19) performed cholecystectomy with resection of segments 4b and 5. In T4, majority of the centers (12-14/19) chose palliative/oncological care. The centers in Sweden extended lymphadenectomy beyond the hepatoduodenal ligament, whereas all other Nordic centers usually limited lymphadenectomy to the hepatoduodenal ligament. All Nordic centers except those in Norway used adjuvant chemotherapy routinely for GBC. There were no major differences between the Nordic centers in diagnostics and follow-up.

Conclusions: The surgical and oncological treatment strategies of GBC vary considerably between the Nordic centers and countries.

Place, publisher, year, edition, pages
Sage Publications, 2023. Vol. 112, no 3, p. 147-156
Keywords [en]
Survey, biliary tract, neoplasm, MDT, resectability
National Category
Cancer and Oncology Surgery
Identifiers
URN: urn:nbn:se:umu:diva-217875DOI: 10.1177/14574969231181228ISI: 001018537600001PubMedID: 37377127Scopus ID: 2-s2.0-85164399012OAI: oai:DiVA.org:umu-217875DiVA, id: diva2:1819044
Available from: 2023-12-13 Created: 2023-12-13 Last updated: 2024-01-25Bibliographically approved

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Hemmingsson, Oskar

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SurgeryWallenberg Centre for Molecular Medicine at Umeå University (WCMM)
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