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Left ventricular hypertrophy: an ECG-based study of prevalence and risk factors in a multiethnic population
Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin.
Public Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland; Department of Public Health, University of Helsinki, Helsinki, Finland.
Department of Diabetes, Central Clinical School, Monash University, VIC, Melbourne, Australia.
Institute of Cardiology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
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2023 (Engelska)Ingår i: Open heart, E-ISSN 2053-3624, Vol. 10, nr 2, artikel-id e002495Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Background: Left ventricular hypertrophy (LVH) is frequently seen in association with arterial hypertension and indicates poor prognosis. This study aimed to determine the prevalence of LVH and associated factors in a multiethnic population from Mauritius.

Methods: Population-based health surveys were performed in 2009 and 2015 and included in total 8961 individuals aged 35–75 years with recorded 12-lead ECG. LVH was defined according to three criteria: Sokolow-Lyon, Cornell voltage and Cornell product. Data were collected about health and lifestyle behaviour. Anthropometry and blood pressure were measured. Fasting levels of blood lipids and glucose were determined, oral glucose tolerance test was performed in people without glucose-lowering medications.

Results: The age-standardised prevalence of LVH was 9% (n=875) according to any of the three ECG criteria. Individuals with LVH were older, more likely to have hypertension, diabetes, known cardiovascular disease (CVD) and elevated levels of cholesterol and creatinine. Further, they were more likely to be of African descent (Creole) and have lower educational level. In a multivariable model, Creole (OR (95% CI)) (1.56 (1.33 to 1.83)), low educational level (1.49 (1.28 to 1.75)), hypertension (3.01 (2.55 to 3.56)), known CVD (1.42 (1.11 to 1.83)) and elevated creatinine (1.08 (1.03 to 1.14)) remained associated with LVH. Individuals with non-treated or uncontrolled hypertension had a higher risk for LVH (3.09 (95% CI 2.57 to 3.71) and 4.07 (95% CI 3.29 to 5.05), respectively), than individuals with well controlled hypertension or normotension.

Conclusion: LVH occurs more frequently in individuals with hypertension, as well as in individuals with African ancestry and/or low education level.

Ort, förlag, år, upplaga, sidor
BMJ Publishing Group Ltd, 2023. Vol. 10, nr 2, artikel-id e002495
Nationell ämneskategori
Kardiologi
Identifikatorer
URN: urn:nbn:se:umu:diva-217534DOI: 10.1136/openhrt-2023-002495ISI: 001102573300003PubMedID: 37935562Scopus ID: 2-s2.0-85177882151OAI: oai:DiVA.org:umu-217534DiVA, id: diva2:1819485
Forskningsfinansiär
Umeå universitetRegion Västerbotten, RV- 967561Hjärt-Lungfonden, 20130630Tillgänglig från: 2023-12-14 Skapad: 2023-12-14 Senast uppdaterad: 2024-04-08Bibliografiskt granskad

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Taki, HinaSöderberg, StefanNilsson, Ulf

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