Umeå University's logo

umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Long-term follow-up of tamoxifen treatment and the use of imaging in psammocarcinoma: a case report, review of the literature and discussion of diagnostic and therapeutic challenges
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Obstetrics and Gynecology. Center of Obstetrics and Gynecology, Umeå University Hospital, Umeå, Sweden.
Umeå University, Faculty of Medicine, Department of Radiation Sciences, Oncology.
Umeå University, Faculty of Medicine, Department of Radiation Sciences, Diagnostic Radiology.ORCID iD: 0000-0002-0943-8178
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Obstetrics and Gynecology.
2023 (English)In: Current Oncology, ISSN 1198-0052, E-ISSN 1718-7729, Vol. 30, no 12, p. 10260-10271Article in journal (Refereed) Published
Abstract [en]

Psammocarcinoma (PsC) represents a rare form of low-grade serous tumor of the ovary or peritoneum. Although ovarian cancer generally has a poor prognosis in its late stages, PsC seems to have a more indolent course. We present a patient with a history of unspecific abdominal pain for more than a year, with sudden acute onset of severe inguinal pain. On admission to the hospital, a computed tomography (CT) revealed a pelvic mass of suspected ovarian origin. Radical surgery was attempted but not achieved due to widespread tumor growth. Histopathological evaluation revealed estrogen receptor-positive stage III PsC. Tamoxifen treatment was thus initiated, still maintaining stable disease 10 years later. The patient has undergone extensive radiological work-up, including CT, chest X-ray, 18F-fluoro-deoxy-glucose positron emission tomography (PET)/CT, 99mTc- hydroxymethylene diphosphonate (HDP) bone scintigraphy, 18F-fluoro-thymidine (FLT) PET/CT, Tc-99m depreotide scintigraphy and magnetic resonance imaging. In conclusion, we demonstrate that PsC has characteristic radiological features and different imaging modalities can be suitable in different clinical situations. In contrast to most other ovarian cancers, PsC does not always warrant adjuvant chemotherapy, even in advanced stages. This emphasizes the need for a deeper knowledge of the biological behavior of this rare tumor, to select the optimal treatment strategy.

Place, publisher, year, edition, pages
MDPI, 2023. Vol. 30, no 12, p. 10260-10271
Keywords [en]
case report, CT, FDG PET, imaging, MRI, ovarian cancer, psammocarcinoma, psammoma bodies, serous carcinoma, tamoxifen
National Category
Radiology, Nuclear Medicine and Medical Imaging Cancer and Oncology
Identifiers
URN: urn:nbn:se:umu:diva-219099DOI: 10.3390/curroncol30120747PubMedID: 38132381Scopus ID: 2-s2.0-85180702524OAI: oai:DiVA.org:umu-219099DiVA, id: diva2:1826042
Funder
Umeå UniversityAvailable from: 2024-01-10 Created: 2024-01-10 Last updated: 2024-07-02Bibliographically approved

Open Access in DiVA

fulltext(1931 kB)46 downloads
File information
File name FULLTEXT01.pdfFile size 1931 kBChecksum SHA-512
11fe3a0513f4666a92894a65c375c3ac32ab40a12c49a49163d78078d793914113d6b72cb404cbaeecbbccbc1d3acc450a53a4a04efcd937bcc359ffe8b92853
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMedScopus

Authority records

Gideonsson, IdaIsraelsson, PernillaStrandberg, SaraOttander, Ulrika

Search in DiVA

By author/editor
Gideonsson, IdaIsraelsson, PernillaStrandberg, SaraOttander, Ulrika
By organisation
Obstetrics and GynecologyOncologyDiagnostic Radiology
In the same journal
Current Oncology
Radiology, Nuclear Medicine and Medical ImagingCancer and Oncology

Search outside of DiVA

GoogleGoogle Scholar
Total: 46 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 197 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf