Reporting essentials for DElirium bioMarker studies (REDEEMS): explanation and elaborationOslo Delirium Research Group, Department of Geriatric Medicine, Oslo, Norway; Oslo University Hospital, Oslo, Norway.
Trinity Biomedical Sciences Institute; Trinity College Institute of Neuroscience, Trinity College, Dublin.
John Hopkins University School of Medicine, Baltimore, MD, USA.
Indiana University School of Medicine, Indianapolis, IN, USA; Indiana University School of Medicine, Indianapolis, IN, USA.
Mayo Clinic, Department of Nursing, Division of Nursing Research, Rochester, MN, USA; Indiana University, School of Medicine, Center for Health Innovation and Implementation Science, USA; Center for Aging Research, Regenstrief Institute, USA.
University of Sydney, Camperdown, Sydney, NSW, Australia; Royal Prince Alfred Hospital, Camperdown, Sydney, NSW, Australia.
University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Department of Anesthesiology, University Hospital Basel and Department of Clinical Research, University of Basel, Basel, Switzerland.
Beth Israel Deaconess Medical Centre, Boston, Massacheusetts, USA; Harvard Medical School, Boston, Massacheusetts, USA; Harvard T.H Chan, School of Public Health, Boston, Massacheusetts, USA.
University of Technology Sydney, IMPACCT (Improving Palliative, Aged and Chronic Care through Clinical Research and Translation), Sydney, NSW, Australia; South West Sydney Clinical School, University of New South Wales, Liverpool, New South Wales, Australia; Ingham Institute of Applied Medical Research, Liverpool, New South Wales, Australia.
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2022 (Engelska)Ingår i: Delirium Communications, ISSN 2959-104XArtikel i tidskrift (Refereegranskat) Published
Abstract [en]
Despite many studies of potential delirium biomarkers, delirium pathophysiology remains unclear. Evidence shows that the quality of reporting delirium biomarker studies is sub-optimal. Better reporting of delirium biomarker studies is needed to understand delirium pathophysiology better. To improve robustness, transparency and uniformity of delirium biomarker study reports, the REDEEMS (Reporting Essentials for DElirium bioMarker Studies) guideline was developed by an international group of delirium researchers through a three-stage process, including a systematic review, a three-round Delphi study, and a follow-up consensus meeting. This process resulted in a 9-item guideline to inform delirium fluid biomarker studies. To enhance implementation of the REDEEMS guideline, this Explanation and Elaboration paper provides a detailed explanation of each item. We anticipate that the REDEEMS guideline will help to accelerate our understanding of delirium pathophysiology by improving the reporting of delirium biomarker research and, consequently the capacity to synthesise results across studies.
Ort, förlag, år, upplaga, sidor
European Delirium Association , 2022.
Nyckelord [en]
Delirium. Reporting Guifeline, Explanation and Elaboration, Biomarkers, Pathophysiology, REDEEMS
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URN: urn:nbn:se:umu:diva-221952DOI: 10.56392/001c.57389OAI: oai:DiVA.org:umu-221952DiVA, id: diva2:1843785
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Published 2022-12-21
2024-03-122024-03-122024-03-12Bibliografiskt granskad