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Safe and efficient practice of parenteral nutrition in neonates and children aged 0–18 years – The role of licensed multi-chamber bags
Baxter R&D Europe, Braine-l'Alleud, Belgium; University of Liège, Liège, Belgium.
Department of Pediatrics - Neonatology, Amsterdam UMC, University of Amsterdam, Emma Children's Hospital, Amsterdam, Netherlands; Amsterdam Reproduction and Development and Amsterdam Gastroenterology Endocrinology Metabolism Research Institutes, Amsterdam, Netherlands.
Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap.ORCID-id: 0000-0002-0726-7029
Instituto de Investigación Sanitaria del Hospital Universitario La Paz – IdiPAZ, (Hospital Universitario La Paz – Universidad Autónoma de Madrid), Madrid, Spain.
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2024 (Engelska)Ingår i: Clinical Nutrition, ISSN 0261-5614, E-ISSN 1532-1983, Vol. 43, nr 7, s. 1696-1705Artikel, forskningsöversikt (Refereegranskat) Published
Abstract [en]

Parenteral nutrition (PN) is recognized as a complex high-risk therapy. Its practice is highly variable and frequently suboptimal in pediatric patients. Optimizing care requires evidence, consensus-based guidelines, audits of practice, and standardized strategies. Several pediatric scientific organizations, expert panels, and authorities have recently recommended that standardized PN should generally be used over individualized PN in the majority of pediatric patients including very low birth weight premature infants. In addition, PN admixtures produced and validated by a suitably qualified institution are recommended over locally produced PN. Licensed multi chamber bags are standardized PN bags that comply with Good Manufacturing Practice and high-quality standards for the finished product in the frame of their full manufacturing license. The purpose of this article is to review the practical aspects of PN and the evidence for using such multi-chamber bags in pediatric patients. It highlights the safety characteristics and the limitations of the different PN practices and provides some guidance for ensuring safe and efficient therapy in pediatric patients.

Ort, förlag, år, upplaga, sidor
Elsevier, 2024. Vol. 43, nr 7, s. 1696-1705
Nyckelord [en]
Multi-chamber bag, Parenteral nutrition, Patient safety, Pediatrics, Preterm infants, Standardization
Nationell ämneskategori
Pediatrik
Identifikatorer
URN: urn:nbn:se:umu:diva-225850DOI: 10.1016/j.clnu.2024.05.023PubMedID: 38823267Scopus ID: 2-s2.0-85194699111OAI: oai:DiVA.org:umu-225850DiVA, id: diva2:1867341
Tillgänglig från: 2024-06-10 Skapad: 2024-06-10 Senast uppdaterad: 2024-06-10Bibliografiskt granskad

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