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Early diet and the risk of coeliac disease. An update 2024 position paper by the ESPGHAN special interest group on coeliac disease
Department of Paediatrics, The Medical University of Warsaw, Warsaw, Poland.
Institute of Gastroenterology, Nutrition and Liver Disease, Schneider Children's Medical Center of Israel, School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Department of Translational Medical Sciences and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy.
Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Pediatrik.
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2024 (Engelska)Ingår i: Journal of Pediatric Gastroenterology and Nutrition - JPGN, ISSN 0277-2116, E-ISSN 1536-4801, Vol. 79, nr 2, s. 438-445Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

This position paper by the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) Special Interest Group on Coeliac Disease (SIG-CD) presents an update to the 2016 recommendations concerning early diet and the risk of coeliac disease (CD). This update adheres to the policy that mandates reviewing guidelines every 5 years, particularly when new data emerge. The 2024 statements and recommendations are essentially similar to the 2016 recommendations. Breastfeeding, whether any amount, exclusive, or of any duration, does not reduce the risk of developing CD. Introducing gluten into an infant's diet at any time between completed 4 months (≥17 weeks) and 12 months of age does not affect the cumulative incidence of CD, although earlier introduction may lead to earlier seroconversion and CD. In observational studies involving cohorts with a known risk for CD, consuming a high amount of gluten compared to a low amount during weaning and in the subsequent childhood years—specifically the first 2–3 years, and even up to 5 years in some studies—was associated with an increased risk for CD. However, the specific optimal amounts of gluten consumption remain undetermined due to insufficient evidence on safe thresholds, and the impact of restricting gluten in the diet of healthy children of unknown risk for CD is unknown. Thus, any recommendation on the gluten amount is currently unjustifiable for the general population and infants with known HLA risk types. There is no specific guidance on the type of gluten-containing foods to be introduced at weaning.

Ort, förlag, år, upplaga, sidor
John Wiley & Sons, 2024. Vol. 79, nr 2, s. 438-445
Nyckelord [en]
coeliac disease risk, gluten amount, gluten introduction, infant feeding, infant nutrition
Nationell ämneskategori
Gastroenterologi och hepatologi Pediatrik
Identifikatorer
URN: urn:nbn:se:umu:diva-227259DOI: 10.1002/jpn3.12280ISI: 001241583300001PubMedID: 38847232Scopus ID: 2-s2.0-85195564954OAI: oai:DiVA.org:umu-227259DiVA, id: diva2:1878775
Tillgänglig från: 2024-06-27 Skapad: 2024-06-27 Senast uppdaterad: 2025-02-11Bibliografiskt granskad

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Chmielewska, Anna

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