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CellSpot: deep learning-based efficient cell center detection in microscopic images
German Research Center for Artificial Intelligence (DFKI) GmbH, Kaiserslautern, Germany; RPTU Kaiserslautern–Landau, Kaiserslautern, Germany.
Sartorius, BioAnalytics, Royston, United Kingdom.
Sartorius, Corporate Research, Royston, United Kingdom.
Umeå University, Faculty of Science and Technology, Department of Chemistry. Computational Life Science Cluster (CLiC), Umeå University, Umeå, Sweden; Sartorius Corporate Research, Umeå, Sweden.ORCID iD: 0000-0003-3799-6094
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2024 (English)In: Artificial Neural Networks and Machine Learning – ICANN 2024: 33rd International Conference on Artificial Neural Networks, Lugano, Switzerland, September 17–20, 2024, Proceedings, Part VIII, Springer Nature, 2024, p. 215-229Conference paper, Published paper (Refereed)
Abstract [en]

Cells play a fundamental role in sustaining life by performing numerous functions crucial for the survival of living organisms. The detection of cells holds paramount importance in the validation and analysis of biological hypotheses, as it offers valuable insights into the behavior, function, diagnosis, and treatment of diseases. By accurately detecting and studying cells, researchers can unravel the complexities of cellular processes, leading to advancements in understanding diseases and the development of effective therapeutic interventions. In the domain of microscopic image analysis, substantial efforts have been devoted to the quantification of cells through segmentation masks and bounding boxes. However, these methods are time-consuming and resource-intensive. To tackle this challenge, we’ve introduced a novel approach focused on cell detection using solely their centerpoints. The proposed pipeline drastically cuts down on annotation efforts while still delivering commendable performance. By leveraging the proposed method, we aim to enhance efficiency in cell detection, paving the way for more expedient and resource-effective analysis in biological research and medical diagnostics.

Place, publisher, year, edition, pages
Springer Nature, 2024. p. 215-229
Series
Lecture Notes in Computer Science, ISSN 0302-9743, E-ISSN 1611-3349
Keywords [en]
cell centroid, cell detection, deep learning, point annotation
National Category
Computer graphics and computer vision
Identifiers
URN: urn:nbn:se:umu:diva-230592DOI: 10.1007/978-3-031-72353-7_16ISI: 001331897100016Scopus ID: 2-s2.0-85205302583ISBN: 978-3-031-72352-0 (print)ISBN: 978-3-031-72353-7 (electronic)OAI: oai:DiVA.org:umu-230592DiVA, id: diva2:1904043
Conference
33rd International Conference on Artificial Neural Networks, ICANN 2024, Lugano, Sweitzerland, September 17-20, 2024
Note

Included in the following conference series: International Conference on Artificial Neural Networks

Available from: 2024-10-08 Created: 2024-10-08 Last updated: 2025-04-24Bibliographically approved

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Trygg, Johan

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