The differentiation antigen Ly-6E.1 is expressed in mouse metastatic tumor cell lines
1997 (Engelska)Ingår i: FEBS Letters, ISSN 0014-5793, E-ISSN 1873-3468, Vol. 403, nr 2, s. 181-185Artikel i tidskrift (Refereegranskat) Published
Abstract [en]
We report the cloning of the mouse surface GPI-anchored Ly-6E.1 protein from a highly metastatic mouse adenocarcinoma cell line CSML-100 by differential display. The expression is specific for the metastatic cell line as the closely related, non-metastatic mouse adenocarcinoma cell line CSML-0 does not express Ly-6E.1. Northern blot analysis reveals expression in a number of mouse tumour cell lines, exclusively metastatic ones. To date, active Ly-6A/E has only been described in lymphoid cells. The correlation between Ly-6E.1 expression, and the ability to metastasize, is discussed.
Ort, förlag, år, upplaga, sidor
John Wiley & Sons, 1997. Vol. 403, nr 2, s. 181-185
Nyckelord [en]
Tumor progression, Ly-6E.l, Metastasis, Adhesion, Differential display
Nationell ämneskategori
Medicinska och farmaceutiska grundvetenskaper Biologiska vetenskaper
Identifikatorer
URN: urn:nbn:se:umu:diva-230657DOI: 10.1016/S0014-5793(97)00050-1ISI: A1997WJ75700015PubMedID: 9042962Scopus ID: 2-s2.0-0031052752OAI: oai:DiVA.org:umu-230657DiVA, id: diva2:1904232
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