This introduction to the Routledge Handbook on Spaces of Mental Health and Wellbeing positions the chapters to come within the disciplinary context of human geography. A brief overview of the emergence of mental health geography as a subfield of research is provided before considering how recent work in this subfield is influenced by theoretical developments in health geography. The ways in which these theoretical developments prompt a re-thinking of mental health and wellbeing as concepts is also discussed before presenting some highlights from the handbook’s main sections - (1) green/blue spaces, (2) lived and embodied spaces, (3) creative spaces, (4) spaces of work and home, and (5) institutional and post-institutional spaces.