In the second half of the twentieth century, the car industry became a lightning rod for debates about human contributions to climate change. Widespread motorisation galvanised the green movements of the 1960s and 1970s, regulators increasingly demanded the use of pollution and climate mitigation technologies, and carmakers responded to this changing consumer and regulatory environment by gradually observing stricter emissions standards and innovating away from combustible engines at the turn of the millennium. This chapter traces the arc of the relationship between car manufacturing and climate change through a business historical lens, from the development of internal combustion engines and their alternatives to the political economy of an energy transition and the decision to prioritise electric vehicles. This analysis aims to lay a foundation for further historical research on car manufacturing and climate change.