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Theory of host-microbe symbioses: challenges and opportunities
Section of Genetic Medicine, Department of Medicine, University of Chicago, IL, Chicago, United States.
Center for Microbial Dynamics and Infection, Georgia Institute of Technology, GA, Atlanta, United States; School of Biological Sciences, Georgia Institute of Technology, GA, Atlanta, United States.
Hawaiʻi Institute of Marine Biology, University of Hawaiʻi at Mānoa, HI, Kāneʻohe, United States.
Department of Ecology, Evolution and Marine Biology, University of California Santa Barbara, CA, Santa Barbara, United States.
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2025 (English)In: Cell Host and Microbe, ISSN 1931-3128, E-ISSN 1934-6069, Vol. 33, no 7, p. 1052-1056Article in journal (Refereed) Published
Abstract [en]

Growing insight into microbial symbioses highlights the need to model these systems mathematically. We discuss three areas requiring theoretical advancement: nested ecology within a host or holobiont, holobiont population dynamics, and symbiont-mediated speciation. Developing the proposed frameworks will bridge theory and empirical findings, accelerating our understanding of host-microbe symbioses.

Place, publisher, year, edition, pages
Cell Press, 2025. Vol. 33, no 7, p. 1052-1056
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Ecology
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URN: urn:nbn:se:umu:diva-242038DOI: 10.1016/j.chom.2025.05.001ISI: 001532821600001PubMedID: 40639335Scopus ID: 2-s2.0-105009508039OAI: oai:DiVA.org:umu-242038DiVA, id: diva2:1982625
Available from: 2025-07-08 Created: 2025-07-08 Last updated: 2025-09-30Bibliographically approved

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Souza, Lucas S.

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