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Long-term evaluation of periprosthetic bone changes in ultra-short versus conventional stems in total hip arthroplasty: a 10-year follow-up of a randomised controlled trial
Division of Orthopaedics, Department of Clinical Sciences at Danderyd Hospital, Karolinska Institute, Stockholm, Sweden.
Division of Orthopaedics, Department of Clinical Sciences at Danderyd Hospital, Karolinska Institute, Stockholm, Sweden.
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences, Orthopaedics.ORCID iD: 0000-0002-5469-2730
Division of Orthopaedics, Department of Clinical Sciences at Danderyd Hospital, Karolinska Institute, Stockholm, Sweden.
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2026 (English)In: HIP International, ISSN 1120-7000, E-ISSN 1724-6067, Vol. 36, no 1, p. 55-63Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Short stems in total hip arthroplasty (THA) have the potential to improve periprosthetic bone preservation compared to conventional stems due to a more anatomical distribution of biomechanical force. This study is a follow-up study of a randomised controlled trial using ultra-short and conventional stems in THA with the aim to investigate the long-term changes in periprosthetic bone mineral density (BMD) at 6 and 10 years post-THA.

METHODS: A cohort of 51 patients with hip osteoarthritis were randomized to either an ultra-short stem (n = 26) or a conventional stem (n = 25) group. Periprosthetic BMD was measured at 6- and 10-years post-surgery. Primary endpoint was BMD changes in Gruen zones 1 and 7. Lumbar spine, L1-4, BMD was used as an indicator of overall bone loss. Clinical outcome scores and BMD changes in Gruen zone 1-7 were used as secondary endpoints.

RESULTS: 37 hips, 17 ultra-short stems and 20 conventional stems, were followed up until 10 years. At 6- and 10-years post-THA, the ultra-short stem group had less periprosthetic BMD reduction compared to the conventional stem group in Gruen zone 1; mean differences (%) were -17.6 (CI, -23.4--10.6) and -18.3 (CI, -28.0--9.0), respectively (p < 0.001). There was similar BMD loss in Gruen zone 7 and zones 1-7 between groups. Compared to overall bone loss, the ultra-short stem group lost less BMD than the conventional group. Adverse events and clinical outcomes did not differ between groups.

CONCLUSIONS: Over a 10-year follow-up, THA using an ultra-short stem exhibited significantly reduced periprosthetic BMD loss in Gruen zone 1 compared to the conventional stem but this did not result in better clinical results. The observed preservation of bone density suggests potential long-term advantages of the ultra-short stem in minimising stress shielding and maintaining periprosthetic bone quality.

TRIAL REGISTRATION: ClinicalTrials.gov registration (number NCT01319227).

Place, publisher, year, edition, pages
Sage Publications, 2026. Vol. 36, no 1, p. 55-63
Keywords [en]
Conventional stem, THA, femoral stem, long-term follow-up, periprosthetic bone mineral density, ultra-short stem
National Category
Orthopaedics
Identifiers
URN: urn:nbn:se:umu:diva-247883DOI: 10.1177/11207000251371283ISI: 001642194800001PubMedID: 41410176Scopus ID: 2-s2.0-105025027692OAI: oai:DiVA.org:umu-247883DiVA, id: diva2:2023820
Funder
Åke Wiberg FoundationLoo och Hans Ostermans Stiftelse för medicinsk forskningRegion StockholmKarolinska InstituteAvailable from: 2025-12-22 Created: 2025-12-22 Last updated: 2026-03-23Bibliographically approved

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