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Sexual functioning after the age of 40 in adults with moderate or severe congenital heart disease
Umeå University, Faculty of Medicine, Department of Diagnostics and Intervention. Region Västra Götaland, Sahlgrenska University Hospital, Children’s Heart Center, Gothenburg, Sweden.
Umeå University, Faculty of Medicine, Department of Nursing.ORCID iD: 0000-0001-6321-8240
Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden.
Department of Cardiology, Skåne University Hospital, Clinical Sciences, Lund University, Lund, Sweden.
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2026 (English)In: International Journal of Cardiology Congenital Heart Disease, E-ISSN 2666-6685, Vol. 24, article id 100664Article in journal (Refereed) Published
Abstract [en]

Background: Sexual health and functioning are significant, yet often overlooked, components of psychosocial well-being of adults with congenital heart disease (ACHD). Prior research reports inconsistent findings, limited data on older adults with CHD, and few studies have compared patients with controls from the general population. This study investigated sexual functioning in middle-aged and elderly ACHD patients and compared it with controls.

Methods: This was a Swedish sub-study of the international APPROACH-IS II project . Patients 40 years or older with moderate or severe CHD were recruited along with controls from the general Swedish population. The design was case control. Erectile dysfunction (ED) in males was assessed using the International Index of Erectile Function. Sexual dysfunction (SD) in females was assessed using the Female Sexual Function Index.

Results: Overall, 146 individuals were included in the study; 90 patients with CHD and 56 controls. Among males, the prevalence of ED was higher in patients (n=57) than in controls (n=37), (21% vs. 2.7%, p=0.01). ED was associated with increasing age (OR=1.11; 95% CI 1.03-1.20). Among females, no difference in the prevalence of SD was observed between patients (n= 33) and controls (n=19) (27% vs. 30%, p=0.76)

Conclusion: Sexual dysfunction was more common in male patients than controls, whereas no differences were observed between female patients and controls. Given that approximately one in five males and one in four females with CHD reported sexual dysfunction, increased empirical and clinical attention is warranted.

Place, publisher, year, edition, pages
Elsevier, 2026. Vol. 24, article id 100664
Keywords [en]
Heart defects, Congenital, Aging, Sexual Health, Sexual Dysfunction, Physiological, Dysfunction, Erectile
National Category
Cardiology and Cardiovascular Disease Nursing
Identifiers
URN: urn:nbn:se:umu:diva-250630DOI: 10.1016/j.ijcchd.2026.100664ISI: 001719541700001PubMedID: 41869685Scopus ID: 2-s2.0-105032543059OAI: oai:DiVA.org:umu-250630DiVA, id: diva2:2042971
Funder
Swedish Heart Lung Foundation, 20190525Visare NorrUmeå UniversityRegion VästerbottenSwedish Heart Lung Foundation, 20240188Available from: 2026-03-03 Created: 2026-03-03 Last updated: 2026-04-17Bibliographically approved

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Dalman-Skogby, SandraBay, AnnikaSandberg, CamillaJohansson, Bengt

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International Journal of Cardiology Congenital Heart Disease
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