Using data generated by a global Delphi study involving international business (IB) scholars and practitioners, this article reflects on the core and domain of a discipline that, on one side, has to deal with increasing competition from related disciplines, which internationalize their research focus, and, on the other side, is trying to develop conceptual knowledge to explain ever more complex international phenomena. Generating a multilevel framework of important issues for IB leads to propositions, which may widen the focus of the discipline to go beyond the firm, which, comparing IB to related disciplines, can provide pathways that maintain IB highly relevant for most diverse communities affected by international business.