In recent years an increasing interest has been directed towards evolutionary processes of economic change following the notion that history matters for future development. These studies put special emphasis on how the spatial structures of the economy emerge from the micro-behaviours of economic agents (often firms). It this paper we argue that while such an approach indeed may provide new and novel insights on the uneven process of economic change, one important aspect of the economy tend to be neglected, namely the spatial behavior and restrictions of people. In this paper, we therefore outline the ideas to a theoretical framework which more thorough integrates evolutionary economic geography with the time-geographical contribution provided by Torsten Hägerstrand and his adherents in order to provide a synthesis between the interdependent dynamic processes occurring in and between place-specific institutions, firms and people. The paper is structured as followed: First, a critical appraisal of recent evolutionary contributions is presented. This is followed by a discussion on the developments made in time-geography the last couple of decades. The paper ends with a concluding section and an empirical example showing that modern micro-simulation techniques may provide useful insights to the evolutionary processes shaping economic change. The empirical example is framed in recent studies analyzing knowledge flows via the job mobility of skilled individuals within and between local labour markets in Sweden.