Research in the integration of technology and content knowledge using problem-based learning (PBL) is a challenge. Thus, the aim of this chapter is to describe experiences and lessons learned from integrating ERP-systems (enterprise resource planning systems) into economic topics course using PBL and cases created for the integration of technology and content knowledge in a business school setting. The mission was to develop the economic students’ analyzing abilities using a ERP-system as a pedagogical tool. A summary table describes how problem-based learning and cases were developed and used within collaboration among universities, colleagues, businesses, and students to accomplish integration of both technology and content knowledge. The experience was that students developed abilities to analyze technology from both theory and a deeper understanding of theory by analyzing technology. The lessons learned were that integration of technology and content knowledge using problem based learning and cases is a never-ending cooperative and learning process.