Triple-Helix activities within the center for biomedical engineering and physics (CMTF) have generated growth in academic research as well as industry in Northern Sweden in the field of biomedical engineering. Currently CMTF holds 26 ongoing research projects involving more than 150 researchers. So far a total of eight spin-off companies have resulted from research in CMTF since the year 2000. A researcher-owned company, CMTF Business Development Co Ltd, has been established for business development of the research results from the CMTF, which so far have launched two spin-off companies and 15 new business leads for business development. The activities have also increased the interest for innovations and entrepreneurship among the scientists in the center.