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This paper describes and reflects on a project carried out at the University of Umeå to examine how communication training for pharmacy students can be developed and implemented in three dimensional virtual worlds such as Second Life (SL). Immersive virtual worlds can be used in higher education in a range of disciplinary contexts and for a variety of educational purposes. The present project has focused on communication training for students studying on an online distance programme: Bachelor of Science in Pharmacy at Umeå University, Sweden. The main purpose of the project was to examine how communication training can be designed and implemented in SL and to assess its effectiveness.