Umeå universitets logga

umu.sePublikationer
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Lactobacillus reuteri influences regrowth of mutans streptococci after full-mouth disinfection: a double-blind, randomised controlled trial
Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Tandläkarutbildning.ORCID-id: 0000-0002-5674-8179
Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Tandläkarutbildning.
Umeå universitet, Medicinska fakulteten, Institutionen för odontologi, Tandläkarutbildning.
Visa övriga samt affilieringar
2013 (Engelska)Ingår i: Caries Research, ISSN 0008-6568, E-ISSN 1421-976X, Vol. 47, nr 4, s. 338-345Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

This study assessed whether the persistence of Lactobacillus reuteri DSM 17938 and ATCC PTA 5289 in saliva could delay the regrowth of mutans streptococci (MS) after a full-mouth disinfection with chlorhexidine (CHX). A randomised, double-blind, placebo-controlled study with a 6-week intervention period and 3- and 6-month follow-up was performed. 62 healthy subjects with moderate to high counts of MS were randomly assigned to a test group (n = 32) or a placebo group (n = 30). Before onset of the intervention, subjects received two sessions of professional cleaning, flossing, and application of CHX varnish and rinsed their mouth with a CHX solution between the sessions (2 days). Thereafter, the test group used probiotic lozenges (2/day) containing L. reuteri (DSM 17938 and ATCC PTA 5289; 1 × 108 CFU of each strain), and the placebo group used identical lozenges lacking the lactobacilli. Saliva samples were collected and cultured onto selective media, and isolates of L. reuteri as well as DNA directly extracted from saliva were tested by polymerase chain reaction (PCR) with specific primers. Presence of salivary MS was analysed with a chair-side test. L. reuteri was frequently detected by culture during the intervention period but in only 3 test group subjects at follow-ups. Regrowth of MS statistically significantly differed depending on the presence or absence of L. reuteri DSM 17938 detected by PCR. We conclude that cultivable L. reuteri strains may only sporadically be confirmed after termination of the intervention, but subjects with PCR-detected L. reuteridemonstrated slower regrowth of MS.

Ort, förlag, år, upplaga, sidor
S. Karger, 2013. Vol. 47, nr 4, s. 338-345
Nyckelord [en]
Detection, Lactobacilli, Mutans streptococci, Probiotics

Nationell ämneskategori
Odontologi
Identifikatorer
URN: urn:nbn:se:umu:diva-80078DOI: 10.1159/000347233ISI: 000322932800010PubMedID: 23486236Scopus ID: 2-s2.0-84874804267OAI: oai:DiVA.org:umu-80078DiVA, id: diva2:646371
Tillgänglig från: 2013-09-09 Skapad: 2013-09-09 Senast uppdaterad: 2023-03-24Bibliografiskt granskad

Open Access i DiVA

Fulltext saknas i DiVA

Övriga länkar

Förlagets fulltextPubMedScopus

Person

Vestman, Nelly RomaniHasslöf, PamelaGranström, ElisabethStecksen-Blicks, Christina

Sök vidare i DiVA

Av författaren/redaktören
Vestman, Nelly RomaniHasslöf, PamelaGranström, ElisabethStecksen-Blicks, Christina
Av organisationen
Tandläkarutbildning
I samma tidskrift
Caries Research
Odontologi

Sök vidare utanför DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
Totalt: 414 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf