In this paper I will discuss some consequences and challenges that information technology has brought about in the museum world, and the "nationality" versus "universality" of collections. My point of departure is a set of presuppositions. Firstly, that the museum, as well as museology, is engaged with the sense of Loss and with the problem of collective Experience (Erfahrung) of Time and Reality in western culture, ever since "modernity" entered the scene at the end of the 18th century. The museum is engaged with Absence. It is the House of Lack, seeking to regain and recreate our losses with the aid of objects. Secondly, today a final transition from ontological values – wie es eigentlich gewesen – to phenomenological values has occurred; life and world are explained as culturally and socially constituted phenomena, dependent on the subjective view of the interpreter. Thirdly, in a world that demands all things to be made available to individual experience, the museum institution faces serious challenges and difficulties to survive – to outlive the very historic (industrial) epoch that gave it birth, and which epoch we (the West) now have left behind. Science and technology have also left the territorial Nation State behind and are actively pursuing global virtual networks of knowledge. Human sciences and museums follow – out in the cyberspace, into the universe.