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  • 1. Borneskog, C.
    et al.
    Sydsjö, G.
    Lampic, Claudia
    Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.
    Bladh, M.
    Skoog Svanberg, A.
    Symptoms of anxiety and depression in lesbian couples treated with donated sperm: a descriptive study2013Ingår i: British Journal of Obstetrics and Gynecology, ISSN 1470-0328, E-ISSN 1471-0528, Vol. 120, nr 7, s. 839-846Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVE: To investigate symptoms of anxiety and depression in lesbian couples undergoing assisted reproductive treatment (ART), and to study the relationship of demographic data, pregnancy outcome and future reproductive plans with symptoms of anxiety and depression.

    DESIGN: Descriptive, a part of the prospective longitudinal 'Swedish study on gamete donation'.

    SETTING: All university clinics in Sweden performing gamete donation.

    POPULATION: A consecutive sample of 214 lesbian couples requesting assisted reproduction, 165 of whom participated.

    METHODS: Participants individually completed three study-specific questionnaires and the Hospital Anxiety and Depression Scale (HADS): time point 1 (T1), at commencement of ART; time point 2 (T2), approximately 2 months after treatment; and time point 3 (T3), 2-5 years after first treatment.

    MAIN OUTCOME MEASURES: Anxiety and depression (HADS), pregnancy outcome and future reproductive plans.

    RESULTS: The vast majority of lesbian women undergoing assisted reproduction reported no symptoms of anxiety and depression at the three assessment points. A higher percentage of the treated women, compared with the partners, reported symptoms of anxiety at T2 (14% versus 5%, P = 0.011) and T3 (10% versus 4%, P = 0.018), as well as symptoms of depression at T2 (4% versus 0%, P = 0.03) and T3 (3% versus 0%, P = 0.035). The overall pregnancy outcome was high; almost three-quarters of lesbian couples gave birth 2-5 years after sperm donation treatments. Open-ended comments illustrated joy and satisfaction about family building.

    CONCLUSION: Lesbian women in Sweden reported good psychological health before and after treatment with donated sperm.

  • 2.
    Faulks, Fiona
    et al.
    Judith Lumley Centre, La Trobe University, VIC, Bundoora, Australia.
    Shafiei, Touran
    Judith Lumley Centre, La Trobe University, VIC, Bundoora, Australia.
    McLachlan, Helen
    Judith Lumley Centre, La Trobe University, VIC, Bundoora, Australia.
    Forster, Della
    School of Nursing and Midwifery, La Trobe University, VIC, Bundoora, Australia.
    Mogren, Ingrid
    Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Obstetrik och gynekologi.
    Copnell, Beverley
    School of Nursing and Midwifery, La Trobe University, VIC, Bundoora, Australia.
    Edvardsson, Kristina
    School of Nursing and Midwifery/Judith Lumley Centre, La Trobe University, VIC, Bundoora, Australia.
    Perinatal outcomes of socially disadvantaged women in Australia: a population-based retrospective cohort study2023Ingår i: British Journal of Obstetrics and Gynecology, ISSN 1470-0328, E-ISSN 1471-0528, Vol. 130, nr 11, s. 1380-1393Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objective: To examine the perinatal outcomes of women who experience social disadvantage using population-based perinatal data collected between 1999 and 2016.

    Design: Population-based, retrospective cohort study.

    Setting: Victoria, Australia.

    Population or Sample: A total of 1 188 872 singleton births were included.

    Methods: Cohort study using routinely collected perinatal data. Multiple logistic regression was performed to determine associations between social disadvantage and adverse maternal and neonatal outcomes with confidence limits set at 99%. Time-trend analysis for perinatal outcomes was performed in relation to area-level disadvantage measures.

    Main Outcome Measures: Incidence of maternal admission to intensive care unit (ICU), postpartum haemorrhage (PPH) and caesarean section, perinatal mortality, preterm birth, low birthweight (LBW), and admission to special care nursery/neonatal intensive care unit (SCN/NICU).

    Results: Social disadvantage was associated with higher odds of adverse perinatal outcomes. Disadvantaged women were more likely to be admitted to ICU, have a PPH or experience perinatal mortality (stillbirth or neonatal death) and their neonates were more likely to be admitted to SCN/NICU, be born preterm and be LBW. A persistent social gradient existed across time for the most disadvantaged women for all outcomes except caesarean section.

    Conclusions: Social disadvantage has a marked negative impact on perinatal outcomes. This aligns with national and international evidence regarding the impact of disadvantage. Strategies that improve access to, and reduce fragmentation in, maternity care in addition to initiatives that address the social determinants of health may contribute to improving perinatal outcomes for socially disadvantaged women.

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  • 3.
    Gazeley, Ursula
    et al.
    Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom; Department of Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom.
    Reniers, Georges
    Department of Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom.
    Romero-Prieto, Julio E.
    Department of Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom.
    Calvert, Clara
    Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom; Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
    Jasseh, Momodou
    Medical Research Council Unit The Gambia at LSHTM, Serekunda, Gambia.
    Herbst, Kobus
    Africa Health Research Institute, Durban, South Africa; DSI-MRC South African Population Research Infrastructure Network (SAPRIN), Durban, South Africa.
    Khagayi, Sammy
    Kenya Medical Research Institute – Centre for Global Health Research, Kisumu, Kenya.
    Obor, David
    Kenya Medical Research Institute – Centre for Global Health Research, Kisumu, Kenya.
    Kwaro, Daniel
    Kenya Medical Research Institute – Centre for Global Health Research, Kisumu, Kenya.
    Dube, Albert
    Malawi Epidemiology and Intervention Research Institute, Karonga, Malawi.
    Dheresa, Merga
    School of Nursing and Midwifery, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.
    Kabudula, Chodziwadziwa W.
    MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
    Kahn, Kathleen
    Umeå universitet, Medicinska fakulteten, Institutionen för epidemiologi och global hälsa. MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
    Urassa, Mark
    The Tazama Project, National Institute for Medical Research, Mwanza, Tanzania.
    Nyaguara, Amek
    KEMRI-Wellcome Trust, Kilifi, Kenya.
    Temmerman, Marleen
    Centre of Excellence in Women and Children's Health, Aga Khan University, Nairobi, Kenya.
    Magee, Laura A.
    Department of Women and Children's Health, School of Life Course and Population Sciences, Faculty of Life Science and Medicine, King's College London, London, United Kingdom; Institute of Women and Children's Health, King's College London, London, United Kingdom.
    von Dadelszen, Peter
    Department of Women and Children's Health, School of Life Course and Population Sciences, Faculty of Life Science and Medicine, King's College London, London, United Kingdom; Institute of Women and Children's Health, King's College London, London, United Kingdom.
    Filippi, Veronique
    Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
    Pregnancy-related mortality up to 1 year postpartum in sub-Saharan Africa: an analysis of verbal autopsy data from six countries2024Ingår i: British Journal of Obstetrics and Gynecology, ISSN 1470-0328, E-ISSN 1471-0528, Vol. 131, nr 2, s. 163-174Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objective: To compare the causes of death for women who died during pregnancy and within the first 42 days postpartum with those of women who died between >42 days and within 1 year postpartum.

    Design: Open population cohort (Health and Demographic Surveillance Systems).

    Setting: Ten Health and Demographic Surveillance Systems (HDSS) in The Gambia, Kenya, Malawi, Tanzania, Ethiopia and South Africa.

    Population: 2114 deaths which occurred within 1 year of the end of pregnancy where a verbal autopsy interview was conducted from 2000 to 2019.

    Methods: InterVA5 and InSilicoVA verbal autopsy algorithms were used to attribute the most likely underlying cause of death, which were grouped according to adapted International Classification of Diseases-Maternal Mortality categories. Multinomial regression was used to compare differences in causes of deaths within 42 days versus 43–365 days postpartum adjusting for HDSS and time period (2000–2009 and 2010–2019).

    Main outcome measures: Cause of death and the verbal autopsy Circumstances of Mortality Categories (COMCATs).

    Results: Of 2114 deaths, 1212 deaths occurred within 42 days postpartum and 902 between 43 and 365 days postpartum. Compared with deaths within 42 days, deaths from HIV and TB, other infectious diseases, and non-communicable diseases constituted a significantly larger proportion of late pregnancy-related deaths beyond 42 days postpartum, and health system failures were important in the circumstances of those deaths. The contribution of HIV and TB to deaths beyond 42 days postpartum was greatest in Southern Africa. The causes of pregnancy-related mortality within and beyond 42 days postpartum did not change significantly between 2000–2009 and 2010–2019.

    Conclusions: Cause of death data from the extended postpartum period are critical to inform prevention. The dominance of HIV and TB, other infectious and non-communicable diseases to (late) pregnancy-related mortality highlights the need for better integration of non-obstetric care with ante-, intra- and postpartum care in high-burden settings.

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  • 4. Hussein, Julia
    et al.
    Newlands, D
    D'Ambruoso, Lucia
    Immpact, University of Aberdeen, UK.
    Thaver, I
    Talukder, R
    Besana, G
    Identifying practices and ideas to improve the implementation of maternal mortality reduction programmes: findings from five South Asian countries2010Ingår i: British Journal of Obstetrics and Gynecology, ISSN 1470-0328, E-ISSN 1471-0528, Vol. 117, nr 3, s. 304-313Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVE: The successful implementation of programmes to reduce maternal mortality is constrained by a 'know-do' gap: the disparity between what is known and the application of that knowledge in policy and practice. This study identified innovations, practices and ideas aimed to improve project and programme implementation.

    DESIGN: Cross-sectional.

    SETTING: Five South Asian countries: Afghanistan, Bangladesh, India, Nepal and Pakistan.

    SAMPLE: Sixteen projects and programmes, and 100 key informants.

    METHODS: In-depth review of documents, key informant interviews and focus-group discussions.

    MAIN OUTCOME MEASURES: Innovations and ideas to improve programme implementation, and their perceived effects.

    RESULTS: Delegation of duties to intermediate-level health workers, incentivisation of health workers, providing the means to overcome financial barriers for accessing care, quality improvements and knowledge transfer were examples of ideas put into practice to improve programme implementation. There was a perception that these improved service use and availability, but objective evidence was lacking.

    CONCLUSIONS: Some innovations, practices and ideas are supported by evidence of effect, and could be replicated, whereas others have not been formally evaluated. Testing of these innovations is required before more widespread adoption can be recommended, although experiences should be shared to narrow the 'know-do' gap, even though the evidence on beneficial effects remains unclear.

  • 5. Lundell, I. W.
    et al.
    Frans, O.
    Helstrom, L.
    Hogberg, U.
    Moby, L.
    Nyberg, Sigrid
    Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Obstetrik och gynekologi.
    Poromaa, I. S.
    Sydsjo, G.
    Ohman, S. G.
    Ostlund, I
    Svanberg, A. S.
    Post-traumatic stress disorder among women requesting induced termination of pregnancy: a Swedish multi-centre study2012Ingår i: British Journal of Obstetrics and Gynecology, ISSN 1470-0328, E-ISSN 1471-0528, Vol. 119, nr SI, Suppl 2, s. 2-2Artikel i tidskrift (Övrigt vetenskapligt)
  • 6.
    Lundin, C.
    et al.
    Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden.
    Wikman, A.
    Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden.
    Lampa, E.
    Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
    Bixo, Marie
    Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Obstetrik och gynekologi.
    Gemzell-Danielsson, K.
    Department of Women’s and Children’s Health, Karolinska Institutet, and Karolinska University Hospital, Stockholm, Sweden.
    Wikman, P.
    Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden.
    Ljung, R.
    Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
    Sundström Poromaa, I.
    Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden.
    There is no association between combined oral hormonal contraceptives and depression: a Swedish register-based cohort study2022Ingår i: British Journal of Obstetrics and Gynecology, ISSN 1470-0328, E-ISSN 1471-0528, Vol. 129, nr 6, s. 917-925Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objective: To investigate whether users of hormonal contraceptives (HCs) are at increased risk of depression compared with non-users. Design: Register-based cohort study.

    Setting: Sweden.

    Sample: Women aged 15–25 years between 2010 and 2017 with no prior antidepressant treatment, psychiatric diagnose or contraindication for HCs (n = 739 585).

    Methods: Women with a prescription of HC were identified via the Swedish Prescribed Drug Register (SPDR). Relative risks (RRs) for first depression diagnosis in current HC-users compared with non-users were modelled by Poisson regression. Adjustments included age, medical indication for HC-use and parental history of mental disorders, among others.

    Main outcome measures: Depression, captured by a redeemed prescription of antidepressant treatment, or a first depression diagnosis in the SPDR and the National Patient Register.

    Results: Compared with non-users, women on combined oral contraceptives (COCs) and oral progestogen-only products had lower or no increased risk of depression, relative risk (RR) 0.89 (95% CI 0.87–0.91) and 1.03 (95% CI 0.99–1.06) after adjustments, respectively. Age-stratified analyses demonstrated that COC use in adolescents conferred no increase in risk (RR 0.96, 95% CI 0.93–0.98), whereas use of progestogen-only pills (RR 1.13, 95% CI 1.07–1.19), contraceptive patch/vaginal ring (RR 1.43, 95% CI 1.30–1.58), implant (RR 1.38, 95% CI 1.30–1.45) or a levonorgestrel intrauterine device (RR 1.59, 95% CI 1.46–1.73) were associated with increased risks.

    Conclusions: This study did not find any association between use of COCs, which is the dominating HC in first time users, and depression. Non-oral products were associated with increased risks. Residual confounding must be addressed in the interpretation of the results. Tweetable abstract: There is no association between combined hormonal contraceptives and depression.

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  • 7. McMurray, C.
    et al.
    Jordan, F.
    Olivecrona, Gunilla
    Umeå universitet, Medicinska fakulteten, Institutionen för medicinsk biovetenskap.
    Freeman, D.
    Free fatty acid transfer across the placenta facilitated by lipoprotein lipase and its relationship with fetal adiposity2016Ingår i: British Journal of Obstetrics and Gynecology, ISSN 1470-0328, E-ISSN 1471-0528, Vol. 123, s. 86-86Artikel i tidskrift (Övrigt vetenskapligt)
  • 8.
    Molin, Johanna
    et al.
    Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Obstetrik och gynekologi.
    Vanky, Eszter
    Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway; Department of Obstetrics and Gynaecology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
    Bixo, Marie
    Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Obstetrik och gynekologi.
    Free leptin index, excessive weight gain, and metformin treatment during pregnancy in polycystic ovary syndrome: What about inflammation?2023Ingår i: British Journal of Obstetrics and Gynecology, ISSN 1470-0328, E-ISSN 1471-0528, Vol. 130, nr 7, s. 841-842Artikel i tidskrift (Refereegranskat)
  • 9.
    Molin, Johanna
    et al.
    Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Obstetrik och gynekologi.
    Vanky, Eszter
    Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway; Department of Obstetrics and Gynaecology, St Olav's Hospital, Trondheim University Hospital, Trondheim, Norway.
    Løvvik, Tone S.
    Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway; Department of Obstetrics and Gynaecology, St Olav's Hospital, Trondheim University Hospital, Trondheim, Norway.
    Dehlin, Eva
    Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Obstetrik och gynekologi.
    Bixo, Marie
    Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Obstetrik och gynekologi.
    Gestational weight gain, appetite regulating hormones, and metformin treatment in polycystic ovary syndrome: A longitudinal, placebo-controlled study2022Ingår i: British Journal of Obstetrics and Gynecology, ISSN 1470-0328, E-ISSN 1471-0528, Vol. 129, nr 7, s. 1112-1121Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objective: To explore mechanisms that modulate gestational weight gain (GWG) in women with polycystic ovary syndrome (PCOS) and healthy controls.

    Design: Sub-sample of randomised controlled trials (PCOS) combined with a prospective cohort (controls).

    Setting: Eleven Norwegian, Swedish, and Icelandic hospitals.

    Population: Pregnant women with PCOS treated with metformin (PCOS-M, n = 36) or placebo (PCOS-P, n = 37), and healthy pregnant women (HC, n = 15).

    Methods: Serum levels of the appetite regulating hormones leptin, ghrelin, allopregnanolone, and soluble leptin receptor (sOB-R) were determined in the first and third trimesters.

    Main Outcome Measures: Excessive GWG (eGWG) relative to body mass index according to Institute of Medicine (IOM) guideline. Serum leptin/sOB-R ratio, or free-leptin-index (FLI), as biomarker of leptin sensitivity. Serum ghrelin and allopregnanolone levels.

    Results: The overall prevalence of eGWG was 44% (38/86). Women with eGWG had higher first and third trimester FLI (< 0.001), and lower third trimester allopregnanolone levels (= 0.003) versus women with non-eGWG. The prevalence of eGWG was lower in PCOS-M versus PCOS-P (28% versus 62%, odds ratio = 0.4, 95% CI 0.2–0.8, = 0.005). FLI decreased during pregnancy in PCOS-M (= 0.01), but remained unaltered in PCOS-P and HC. Ghrelin and allopregnanolone levels were comparable in PCOS-M, PCOS-P and HC throughout pregnancy.

    Conclusion: Excessive GWG is associated with enhanced leptin resistance, and attenuated physiological increase in serum allopregnanolone levels during pregnancy. Metformin reduces the risk for eGWG and improves leptin sensitivity in pregnant women with PCOS.

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  • 10.
    Sandström, Anton
    et al.
    Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Obstetrik och gynekologi. Department of Obstetrics and Gynaecology, Sundsvall County Hospital, Sundsvall, Sweden.
    Bixo, Marie
    Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Obstetrik och gynekologi.
    Johansson, Maja
    Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Obstetrik och gynekologi.
    Bäckström, Torbjörn
    Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Obstetrik och gynekologi.
    Turkmen, Sahruh
    Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Obstetrik och gynekologi. Department of Obstetrics and Gynaecology, Sundsvall County Hospital, Sundsvall, Sweden.
    Effect of hysterectomy on pain in women with endometriosis: a population-based registry study2020Ingår i: British Journal of Obstetrics and Gynecology, ISSN 1470-0328, E-ISSN 1471-0528, Vol. 127, nr 13, s. 1628-1635Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objective: To assess pain symptoms before and after hysterectomy in women with endometriosis.

    Design: A population-based registry study.

    Setting: Sweden.

    Population: Women aged 18-45 years who underwent hysterectomy for endometriosis between 2010 and 2015.

    Methods: Pain symptoms before hysterectomy and 12 months after surgery were collected from the Swedish National Quality Register for Gynaecological Surgery (GynOp). Pain symptoms were also assessed by follow-up surveys after a median follow-up period of 63 months.

    Main outcome measures: Pelvic or lower abdominal pain after hysterectomy.

    Results: The study included 137 women. The proportion of women experiencing pain of any severity decreased by 28% after hysterectomy (P < 0.001). The proportion of women with severe pain symptoms decreased by 76% after hysterectomy (P < 0.001). The majority of women (84%) were satisfied with the surgical result. Presence of severe pain symptoms after the hysterectomy was associated with less satisfaction (P < 0.001). Pain symptoms after surgery, patient satisfaction and the patient's perceived improvement were not significantly different between women whose ovarian tissue was preserved and women who underwent bilateral oophorectomy.

    Conclusions: We observed a significant, long-lasting reduction in pain symptoms after hysterectomy among women with endometriosis. Hysterectomy, with the possibility of ovarian preservation, may be a valuable option for women with endometriosis who suffer from severe pain symptoms.

    Tweetable abstract: Hysterectomy is a valuable option for women with endometriosis and severe pain symptoms.

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  • 11. Sydsjö, G.
    et al.
    Lampic, Claudia
    Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden.
    Brändström, S.
    Gudmundsson, J.
    Karlström, P. O.
    Solensten, N. G.
    Thurin-Kjellberg, A.
    Skoog Svanberg, A.
    Personality characteristics in a Swedish national sample of identifiable oocyte donors2011Ingår i: British Journal of Obstetrics and Gynecology, ISSN 1470-0328, E-ISSN 1471-0528, Vol. 118, nr 9, s. 1067-1072Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVE: To study the personality characteristics of identifiable oocyte donors in a national sample in comparison with normal values.

    DESIGN: Descriptive study.

    SETTING: All Swedish donation programmes.

    SAMPLE: In total, 181 women out of 221 donors recruited during 2005-2008.

    METHODS: Standardised questionnaires were used to measure personality characteristics.

    MAIN OUTCOME MEASURE: Demographics, temperament and character inventory (TCI).

    RESULTS: The majority (69%) of the donors had biological children of their own. The results from the TCI indicate that the oocyte donors were all within the normal range of character. With regard to personality, a significant difference was evident between the two groups: oocyte donors showed lower means for harm avoidance and higher scores for persistence than the controls. This indicates that the donors felt less worried, and displayed a lower level of fear of uncertainty, shyness and fatiguability, and a higher level of persistence, than the controls. In the present sample, 29 (16%) of the donors were so-called 'known donors', that is the recipient couples and the donors were known to each other. 'Known donors' displayed a mature and stable character.

    CONCLUSION: We found that the women who had been accepted for inclusion in this nationwide oocyte donor programme were all well adjusted and mature.

  • 12. Sydsjö, G.
    et al.
    Lampic, Claudia
    Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden.
    Brändström, S.
    Gudmundsson, J.
    Karlström, P-O
    Solensten, N. G.
    Thurin-Kjellberg, A.
    Skoog Svanberg, A.
    Who becomes a sperm donor: personality characteristics in a national sample of identifiable donors2012Ingår i: British Journal of Obstetrics and Gynecology, ISSN 1470-0328, E-ISSN 1471-0528, Vol. 119, nr 1, s. 33-39Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVE: To study the personality characteristics of identifiable sperm donors in a national sample in comparison with the same characteristics of a control group.

    DESIGN: Descriptive study.

    SETTING: All clinics (n=7) performing gamete donation in Sweden.

    POPULATION: All Swedish sperm donors recruited during 2005-08. An age-matched group of Swedish men served as controls.

    METHODS: Standardised questionnaires were used to measure personality.

    MAIN OUTCOME MEASURES: Demographics and the Temperament and Character Inventory (TCI).

    RESULTS: The mean age of the donors was 33.8±7.8 years (18-56 years). About one-third (36.5%) of the donors had biological children of their own. With regard to personality, significant differences were present on harm avoidance, with lower means for sperm donors (P=0.002, 95% CI -3.74 to -0.85), and on self-directedness and cooperativeness, with higher means for donors (P=0.002, 95% CI 0.97-4.19; P=0.001; 95% CI 0.75-2.95, respectively), compared with controls. This indicates that the donors in general feel less worried and suffer less from uncertainty, shyness and fatigability than controls. They also perceive themselves as being autonomous, with a capacity to take responsibility, to behave in a goal-directed manner, to be resourceful and self-acceptant, and to behave in a manner guided by meaningful values and goals. Furthermore, they describe themselves as being well integrated in humanity or society, and having a good capacity for identification with and acceptance of other people.

    CONCLUSIONS: The screening process at the clinics seems to generate a group of stable, mature and well-integrated donors, and this is a promising result for the future.

  • 13. Valladares, Eliette
    et al.
    Peña, Rodolfo
    Persson, Lars Ake
    Högberg, Ulf
    Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Epidemiologi och folkhälsovetenskap. Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Obstetrik och gynekologi.
    Violence against pregnant women: prevalence and characteristics. A population-based study in Nicaragua.2005Ingår i: British Journal of Obstetrics and Gynecology, ISSN 1470-0328, E-ISSN 1471-0528, Vol. 112, nr 9, s. 1243-1248Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVE: This study aims to estimate the prevalence and characteristics of partner abuse during pregnancy as well as to investigate associated social factors in León, Nicaragua. DESIGN: Cross-sectional community-based study. SETTING: All pregnant women from 50 randomly selected geographical clusters out of 208 in the municipality of León, Nicaragua. SAMPLE: A total of 478 pregnant women were included; only one woman refused to participate. METHOD: The domestic violence questionnaire from the WHO-co-ordinated Multi-Country Study on Women's Health and Life Events was used with each participant being interviewed twice during pregnancy. MAIN OUTCOME MEASURES: Prevalence and characteristics of partner violence during pregnancy. RESULTS: The prevalence of emotional, physical and sexual abuse during pregnancy was 32.4%, 13.4% and 6.7%, respectively. Seventeen percent reported experience of all three forms of violence. Two-thirds of the victims reported repeated abuse. Half of the abused women had experienced punches and kicks directed towards the abdomen and 93% had been injured. Most women had not sought health care in relation to the abuse, but those who did were usually hospitalised. Factors such as women's age below 20 years, poor access to social resources and high levels of emotional distress were independently associated with violence during pregnancy. CONCLUSION: Violence against pregnant women in Nicaragua is common and often repeated. Although these women have poor access to social resources and high levels of emotional distress, they are rarely assisted by the health services. Innovative strategies are needed to provide support and counselling.

  • 14.
    Waagaard, Lovisa
    et al.
    Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
    Herraiz-Adillo, Ángel
    Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
    Ahlqvist, Viktor H.
    Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
    Higueras-Fresnillo, Sara
    Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden; Department Physical Education, Sport and Human Motricity, Universidad Autónoma de Madrid, Madrid, Spain.
    Berglind, Daniel
    Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden; Centre for Epidemiology and Community Medicine, Region Stockholm, Stockholm, Sweden; Center for Wellbeing, Welfare and Happiness, Stockholm School of Economics, Stockholm, Sweden.
    Wennberg, Patrik
    Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Allmänmedicin.
    Daka, Bledar
    School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
    Lenander, Cecilia
    Department for Clinical Sciences in Malmö, Centre for Primary Health Care Research, Lund University, Lund, Sweden.
    Sundström, Johan
    Clinical Epidemiology Unit, Department of Medical Sciences, Uppsala University, Uppsala, Sweden; The George Institute for Global Health, University of New South Wales, NSW, Sydney, Australia.
    Östgren, Carl Johan
    Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden; Centre for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden.
    Rådholm, Karin
    Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden; The George Institute for Global Health, University of New South Wales, NSW, Sydney, Australia.
    Henriksson, Pontus
    Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
    Body mass index and weight gain in pregnancy and cardiovascular health in middle age: A cohort study2023Ingår i: British Journal of Obstetrics and Gynecology, ISSN 1470-0328, E-ISSN 1471-0528Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objective: To examine associations between body mass index (BMI) in early pregnancy and gestational weight gain (GWG) with cardiovascular health in middle age using the ‘Life's Essential 8’ (LE8) concept of the American Heart Association (AHA).

    Design: Population-based cohort study.

    Setting: Swedish CardioPulmonary bioImage Study (SCAPIS).

    Population: A total of 8871 women from SCAPIS were included.

    Methods: Information on cardiovascular health in middle age was collected from SCAPIS and linked to pregnancy weight data obtained from the Swedish Medical Birth Register, with an average follow-up time of 24.5 years. An LE8 score between 0 and 100 was determined, where a score under 60 points was defined as poor cardiovascular health. Binary logistic regression and restricted cubic splines were used.

    Main outcome measures: Cardiovascular health according to LE8 in middle age.

    Results: The odds of having poor cardiovascular health in middle age were significantly higher in women who had overweight (adjusted odds ratio, aOR 3.30, 95% CI 2.82–3.88) or obesity (aOR 7.63, 95% CI 5.86–9.94), compared with women classified as being of normal weight in pregnancy. Higher odds were also found for excessive GWG (aOR 1.31, 95% CI 1.09–1.57), compared with women who gained weight within the recommendations.

    Conclusions: A high BMI in early pregnancy and excessive GWG were associated with greater odds of poor cardiovascular health in middle age. Although further studies are needed, our results highlight pregnancy as an important period to support long-term cardiovascular health.

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