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  • 1. Bessa, Agustina
    et al.
    Maclennan, Steven
    Enting, Deborah
    Bryan, Richard
    Häggström, Christel
    Umeå University, Faculty of Medicine, Department of Biobank Research.
    Van Hemelrijck, Mieke
    Reply to Jon Mikel Inarritu, Daniele Castellani, and Jeremy YC Teoh's Letter to the Editor re: Agustina Bessa, Steven Maclennan, Deborah Enting, et al. Consensus in Bladder Cancer Research Priorities Between Patients and Healthcare Professionals Using a Four-stage Modified Delphi Method. Eur Urol 2019;76:260-12019In: European Urology, ISSN 0302-2838, E-ISSN 1873-7560, Vol. 76, no 2, p. E45-E46Article in journal (Refereed)
  • 2.
    Russell, Beth
    et al.
    Department of Translational Oncology and Urology Research School of Cancer and Pharmaceutical Sciences King's College London London UK.
    Häggström, Christel
    Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Section of Medicine. Department of Surgical Sciences Uppsala University Uppsala Sweden.
    Holmberg, Lars
    Department of Translational Oncology and Urology Research School of Cancer and Pharmaceutical Sciences King's College London London UK; Department of Surgical Sciences Uppsala University Uppsala Sweden.
    Liedberg, Fredrik
    Department of Urology Skåne University Hospital Malmö Sweden; Institution of Translational Medicine Lund University Malmö Sweden.
    Gårdmark, Truls
    Department of Clinical Sciences Danderyd Hospital, Karolinska Institute Stockholm Sweden.
    Bryan, Richard T
    Institute of Cancer and Genomic Sciences The University of Birmingham Birmingham UK.
    Kumar, Pardeep
    The Royal Marsden NHS Foundation Trust London UK.
    Van Hemelrijck, Mieke
    Department of Translational Oncology and Urology Research School of Cancer and Pharmaceutical Sciences King's College London London UK.
    Systematic review of the association between socioeconomic status and bladder cancer survival with hospital type, comorbidities, and treatment delay as mediators2021In: BJUI Compass, ISSN 2688-4526, Vol. 2, no 3, p. 140-158Article, review/survey (Refereed)
    Abstract [en]

    Objectives:  To review the current evidence on the relationship between three proposed mediators (comorbidities, hospital type, and treatment delays) for the relationship between socioeconomic status (SES) and bladder cancer survival.

    Materials and methods:  Six different searches using OVID (Medline and Embase) were carried out to collate information available between the proposed mediators with both SES and survival in bladder cancer. This systematic review was conducted according to a pre-defined protocol and in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

    Results:  A total of 49 studies were included in the review across the six searches (one appeared in two searches). There was a wealth of studies investigating the relationship between each of the proposed mediators with survival in bladder cancer patients. In general, a higher SES, lower comorbidities, and a larger hospital volume were all found to be associated with a decreased risk of death in bladder cancer patients. There was, however, a paucity of studies investigating the associations between these mediators and SES in bladder cancer patients.

    Conclusions:  To gain a deeper understanding of the relationship between SES and survival identified in several observational studies, further investigations into the relationship between the proposed mediators and SES are warranted. Moreover, modifiable mediators, eg, treatment delay, highlight the importance of the standardization of clinical care across SES groups for all bladder cancer patients.

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