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  • 1.
    Abdullah, Sara Alawi
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Lång respektive fördröjd provtransport ger försämrad blodprovskvalitet2013Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 2.
    Abdulleteef, Lina
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Förekomst av humant papillomvirus i tonsillcancer i norra regionen i Sverige 2000-20122013Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
  • 3.
    Abezie, Henock
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Preanalytisk inverkan av provtagningsrör vid zinkanalys i plasma2020Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 4.
    Abrahamsson, Karolina
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Detektion av herpesvirus i hjärnvävnad med q-PCR: Utvärdering av KAPA Express Extract kit och KAPA PROBE FORCE q-PCR kit2016Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 5.
    Ahmed, Ahmed Hussein Ahmed
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Metodjämförelse mellan laboratoriebaserat instrument och tre patientnära tester vid drogscreening av urin2023Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 6.
    Akula, Ilona
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Hjärtfunktion vid ärftlig transtyretin-amyloidos: Jämförelse av hjärtfrekvensvariabilitet och ekokardiografi mellan två amyloidfibrilltyper2015Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 7.
    Al Rabiey, Ahmed
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Detektion av aktin i paraffinsnitt från human vävnad2015Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 8.
    Alavuotunki, Meiju-Maari
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Utveckling av små heterocykler vilka inhiberar gonokocker, MRSA och VRE2020Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 9.
    Albertsson, Jakob
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science. Umeå University, Faculty of Medicine, Department of Medical Biosciences, Pathology.
    Effekt av förbehandling vid detektion av muterat superoxiddismutas-1 protein: Immunohistokemisk detektion av SOD1 aggregat hos G93A transgena möss2016Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
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  • 10.
    Ali, Jalal
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Fluorescerande Chlamydia trachomatis-mCherry för analys av nya antimikrobiella substanser2016Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 11.
    Ally Lalloo, Arshad
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Mapping the Role of ATP Binding and Hydrolysis of ClpB Domain in Francisella tularensis2017Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 12.
    Al-majidy, Noor
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Odling av humana norovirus med interferonhämmande celler2020Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
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  • 13.
    Almeros, Isak
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Bindning av Adenovirus typ 40 till kommensala grampositiva och gramnegativa bakterier2013Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 14.
    Alverup, Josefin
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Förekomst av bakterier i hudstrukturer med sjukdomen Hidradenitis suppurativa: propionibacterium acnes, Propionibacterium granulosum och Staphylococcus species detektion med immunofluorescens2013Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
  • 15.
    Anderson, Filippa
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Förändrat uttryck av Epidermal Growth Factor Receptors ligander i androgenoberoende prostata-cancer2012Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
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  • 16.
    Andersson, Anna
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Jämförande studie av gelteknik, rörteknik och ORTHO Vision® för reguljär- och irreguljär antikroppstitrering2024Independent thesis Advanced level (professional degree), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    .

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  • 17.
    Andersson, Ida
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science. Umeå University, Faculty of Medicine, Department of Medical Biosciences.
    Etablering av referensmaterial för relativ telomerlängdsmätning med kvantitativ PCR2022Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 18.
    Andersson, Malin
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science. Umeå University, Faculty of Medicine, Department of Integrative Medical Biology (IMB).
    Effekten av extracellulära vesiklar från stamceller ur fettväv för kärlnybildning vid serumfri odling2021Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 19.
    Andersson, Paulina
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Autolog adsorptionsteknik hos nytransfunderad patient med autoantikroppar – en experimentell metodutvärdering.2018Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 20.
    Andersson, Simon
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Binding of Norovirus-Like Particles to Integrin Expressing CHO Cells2017Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 21.
    Andersson, Viktor
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Vänsterkammarfunktion hos cancerpatienter som erhållit hjärttoxisk behandling: Intraobservatörvariabilitet för systoliska funktionsmått utvärderad med ekokardiografi2018Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 22.
    Andersson-Skjaeret, Cassandra
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Genetisk analys av intermediära expansioner av C9orf72 HRE i en svensk ALS-drabbad släkt2023Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 23.
    Andusa Ambele, Carl
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Kombinationsbehandling med antibiotika och kolesterolhämmare mot Staphylococcus epidermidis2022Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 24.
    Arabi, Thyba
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science. Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Medicine.
    Cajal cellernas roll i mag-tarm komplikationer hos patienter med transtyretin amyloidos2017Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 25.
    Arnfjell, Emanuel
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    En arytmijämförelse mellan unga elitidrottare och unga icke idrottande med 24h-Holter2020Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 26.
    Arnqvist, Jennifer
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science. Umeå University, Faculty of Medicine, Department of Medical Biosciences, Pathology.
    Optimering av lymfocytfraktionering med AutoMACS Pro för biobankning av hematologiska maligniteter2015Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
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  • 27.
    Aspelin, Jesper
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Anrikning med Illumina Nextera XT sekvenseringsbibliotek2017Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 28.
    Augustsson Sjögren, Daniel
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Characterisation of aptamers selected for binding to Yersinia pestis virulence protein LcrV2011Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
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  • 29.
    Bakelov, Erik
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Referensvärden med ultraljud på Nervus medianus: Tvärsnittsarea och kvoter hos en ung och subjektivt frisk population2023Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 30.
    Baroshki, Rojan
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Mykofenolsyra och AUC-beräkning för organtransplanterade patienter2015Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 31.
    Baudin, Maria
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Ökad trombopoes och perifer trombocytaktivering i Hantavirus-infekterade patienter2017Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
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  • 32.
    Berg, Johanna
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Visualisering av mikroorganismer i hårfolliklar från patienter med follikulit2012Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
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  • 33.
    Berg, Mari
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science. Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Clinical Bacteriology.
    Utvärdering av Sysmex UF-5000 för snabb antibiotikaresistens­bestämning av bakterier2018Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 34.
    Berggren, Kevin
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Metodvalidering av IGF-1 med ECLIA på Cobas e601 system2019Independent thesis Advanced level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 35.
    Bergkvist, Linn
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Visual Evoked Potentials: Referensvärden och könsskillnader2020Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 36.
    Bergman, Jenny
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    HPA-1a fenotypning av blod- och trombocytgivare: ett metodutvecklingsarbete2024Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 37.
    Bergqvist, Simon
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science. Umeå University, Faculty of Medicine, Department of Medical Biosciences, Clinical chemistry.
    Preanalytisk stabilitet för 25(OH)-vitamin D i koagulerat blod och serum2019Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 38.
    Bergström, Felicia
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science. Umeå University, Faculty of Medicine, Department of Medical Biosciences, Pathology. 9503132624.
    Tumörexosomers effekt på prostataorganoider2020Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 39.
    Birnefeld, Johan
    et al.
    Umeå University, Faculty of Medicine, Department of Clinical Sciences, Neurosciences.
    Hansson, William
    Umeå University, Faculty of Medicine, Department of Clinical Sciences, Neurosciences.
    Larsson, Jenny
    Umeå University, Faculty of Medicine, Department of Clinical Sciences, Neurosciences.
    Björnfot, Cecilia
    Qvarlander, Sara
    Umeå University, Faculty of Medicine, Department of Radiation Sciences, Radiation Physics.
    Wåhlin, Anders
    Umeå University, Faculty of Medicine, Umeå Centre for Functional Brain Imaging (UFBI). Umeå University, Faculty of Science and Technology, Centre for Biomedical Engineering and Physics (CMTF). Umeå University, Faculty of Science and Technology, Department of Applied Physics and Electronics.
    Eklund, Anders
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science. Umeå University, Faculty of Medicine, Umeå Centre for Functional Brain Imaging (UFBI). Umeå University, Faculty of Science and Technology, Centre for Biomedical Engineering and Physics (CMTF). Umeå University, Faculty of Medicine, Department of Radiation Sciences, Radiation Physics.
    Malm, Jan
    Umeå University, Faculty of Medicine, Department of Clinical Sciences, Neurosciences.
    Associations of cerebral arterial pulsatility, clinical symptoms and imaging features of cerebral small vessel diseaseManuscript (preprint) (Other academic)
  • 40.
    Bixo, Mi
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Detektion av alloantikroppar hos nyligt transfunderade DAT-positiva patienter: Utvärdering med en experimentell in vitro modell2018Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 41.
    Björklund Jonasson, Linnea
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Utvärdering av infektiösa Langat viruskloners markörplacering i cellkultur2024Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 42. Björquist, P
    et al.
    Brohlin, Maria
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Ehnebom, J
    Ericsson, M
    Kristiansen, C
    Pohl, G
    Deinum, J
    Plasminogen activator inhibitor type-1 interacts exclusively with the proteinase domain of tissue plasminogen activator.1994In: Biochimica et Biophysica Acta, ISSN 0006-3002, E-ISSN 1878-2434, Vol. 1209, no 2, p. 191-202Article in journal (Refereed)
    Abstract [en]

    Two different techniques have been used to study the complex formation of recombinant human plasminogen activator inhibitor type-1, PAI-1, with either recombinant human two-chain tissue plasminogen activator, tc tPA (EC 3.4.21.68), or the tPA deletion variants tc K2P, containing the kringle 2 domain and the proteinase domain, and P, containing only the proteinase domain. The same value for Kon, 2.10(7) M-1s-1 for binding of PAI-1 was found for the three tPA forms by direct detection of the complex formation in real time by surface plasmon resonance, BIAcore, or indirectly by monitoring the time course of the inhibition of tPA using the chromogenic substrate N-methylsulfonyl-D-Phe-Gly-Arg-4-pNA-acetate. Apparently, no conformational change is involved in the rate-limiting step, since the kon value was found to be independent of the temperature from 20 to 35 degrees C. By the BIAcore technique, it was found that the complex between PAI-1 and tPA covalently coupled to the surface, was stable at 25 degrees C, since no dissociation was seen in buffer. However, extended treatment with 1 M NH4OH destroyed the complex with t 1/2 = 5 h. The same kon values and complex composition were found by measuring either the binding of tPA to PAI-1 captured on the monoclonal antibody MAI-11 or the binding of PAI-1 to tPA captured on the monoclonal antibody 2:2 B10. Quantification of the complex composition between PAI-1 captured on the monoclonal antibody MAI-11 with either tPA, K2P or P gave a one-to-one ratio with the fraction of active PAI-1, consistent with the results from SDS-PAGE and the specific activity of PAI-1. The complexes of the three tPA forms with PAI-1 captured on a large surface of MAI-11 dissociated more rapidly from MAI-11, with the same apparent koff, kdis, = 2.10(-3) s-1, compared with 0.7-10(-3) s-1 for the dissociation of PAI-1 alone. In consistance, the Kd, calculated from the direct determination of the kon and koff for the association of different form of PAI-1 to a small surface of MAI-11, was found to be higher for PAI-1 in complex with tPA than for free active PAI-1. Apparently, upon complex formation, a change is induced in PAI-1 at the binding epitope for MAI-11.(ABSTRACT TRUNCATED AT 400 WORDS)

  • 43.
    Block, Emma
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    En jämförande neurografisk studie: Hur mätparametrar för utvärdering av neurofysiologisk sjukdom påverkas vid olika vinklar på armbågen2019Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 44.
    Blom, Amanda
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    HSP90- och IAP-inhibitor motverkar cisplatinresistens i lungcancerceller2013Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
  • 45.
    Blomdahl, Karin
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Könsskillnader i progress av hjärtengagemang hos patienter med ärftlig transthyretinamyloidos: En studie över tid2015Independent thesis Basic level (professional degree), 180 HE creditsStudent thesis
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  • 46.
    Boklund, Kajsa
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science. Umeå University, Faculty of Medicine, Department of Medical Biosciences, Clinical chemistry.
    Jämförelse av citratkoncentration i koagulationsprovtagningsrör: Jämförelse av citratkoncentrationerna 3,8 % och 3,2 % i koagulationsprovtagningsrör och dess effekter på analysresultat i samband med rörposttransport2014Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 47.
    Boldrup, Linda
    et al.
    Umeå University, Faculty of Medicine, Medical Biosciences, Pathology.
    Coates, Philip J
    Hedberg, Ylva
    Umeå University, Faculty of Medicine, Medical Biosciences, Pathology. Umeå University, Faculty of Medicine, Clinical Microbiology, Biomedical Laboratory Science.
    Sjöström, Björn
    Umeå University, Faculty of Medicine, Clinical Sciences, Otorhinolaryngology.
    Dahlqvist, Åke
    Umeå University, Faculty of Medicine, Clinical Sciences, Otorhinolaryngology.
    Nylander, Karin
    Umeå University, Faculty of Medicine, Medical Biosciences, Pathology.
    Expression of p63, COX-2, EGFR and beta-catenin in smokers and patients with squamous cell carcinoma of the head and neck reveal variations in non-neoplastic tissue and no obvious changes in smokers.2005In: International Journal of Oncology, ISSN 1019-6439, E-ISSN 1791-2423, Vol. 27, no 6, p. 1661-1667Article in journal (Refereed)
    Abstract [en]

    Squamous cell carcinoma of the head and neck (SCCHN), the 6th most common malignancy in the world, is associated with smoking and has a low 5-year survival rate. Various changes have been described at different stages of SCCHN tumour development, including overexpression of p63, a protein important for development of normal epidermal structures. p63 has been suggested to activate beta-catenin, and nuclear accumulation of beta-catenin is an important event in many cancers. Elevated COX-2 activity and overexpression of EGFR protein has been shown in a variety of human cancers, including SCCHN. An important question for the pathogenesis of SCCHN is when the genetic changes take place during the natural course of the disease, and whether they appear in clinically normal oral mucosa to predispose tumour development. We mapped the expression of p63, COX-2, EGFR, beta-catenin, and PP2A in oral mucosa from smokers/non-smokers and from patients with SCCHN. We also considered if changes occurring in tumours are present in the clinically normal tissue adjacent to the tumour. No direct influence of heavy smoking on the levels of the proteins studied could be seen. Tumours and clinically normal non-neoplastic tissue from SCCHN patients showed increased expression of COX-2 and PP2A. Interestingly, non-neoplastic tissue adjacent to SCCHN also showed increased beta-catenin, although this was not seen in tumours. The data support the notion that pre-existing alterations in clinically normal epithelium exist in patients with SCCHN and could be important for the pathogenesis of the disease and for local recurrences.

  • 48.
    Borgstedt, Håkan
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Överföring av Yersinia pseudotuberculosis effektorproteinet YopE till HeLa-celler, mer än en mekanism?2012Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
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  • 49.
    Boström, Emelie
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Validering av kolonn för analys av alkoholer och glykoler med gaskromatografi: Jämförelse av två kolonner samt fortsatt validering för klinisk tillämpning2018Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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  • 50.
    Boström, Markus
    Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Biomedical Laboratory Science.
    Utvärdering av 16S rRNA PCR vid mikrobiologisk diagnostik av misstänkt ortopedisk implantat infektioner2016Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
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